Recombinant Active Human EPCAM Protein, His-tagged(C-ter)
Cat.No. : | EPCAM-66H |
Product Overview : | Recombinant Active Human EPCAM Protein with His tag (C-ter) was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008] |
Source : | E. coli |
Species : | Human |
Tag : | His(C-ter) |
Form : | Powder |
Bio-activity : | Determined by the ability of the immobilized protein to support the adhesion of the 3T3 cells. The ED50 for this effect is 0.2-1.7 ng/mL. |
AA Sequence : | MQEECVCENYKLAVNCFVNNNRQCQ CTSVGAQNTVICSKLAAKCLVMKAE MNGSKLGRRAKPEGALQNNDGLYDP DCDESGLFKAKQCNGTSMCWCVNTA GVRGSKLGRRAKPEGALQNNDGLYD PDCDESGLFKAKQCNGTSMCWCVNT A GVRSILYENNVITIDLVQNSSQKTQNDVDIADVAYYFEKDVKGESLFHS KKMDLTVNGEQLDLDPGQTLIYYVD EKAPEFSMQGLK |
Endotoxin : | Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test. |
Purity : | > 95% (by SDS-PAGE) |
Applications : | SDS-PAGE |
Notes : | For laboratory research only, not for drug, diagnostic or other use. |
Storage : | Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Storage Buffer : | PBS (pH 8.0) |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
Gene Name : | EPCAM epithelial cell adhesion molecule [ Homo sapiens ] |
Official Symbol : | EPCAM |
Synonyms : | EPCAM; epithelial cell adhesion molecule; antigen identified by monoclonal AUA1 , M4S1, MIC18, TACSTD1, tumor associated calcium signal transducer 1; 17 1A; 323/A3; CD326; CO 17A; EGP 2; EGP34; EGP40; Ep CAM; ESA; GA733 2; HEA125; KS1/4; KSA; Ly74; MH99; MK 1; MOC31; TACST 1; TROP1; epithelial glycoprotein 314; human epithelial glycoprotein-2; cell surface glycoprotein Trop-1; adenocarcinoma-associated antigen; tumor-associated calcium signal transducer 1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); M4S1; MK-1; DIAR5; EGP-2; MIC18; EGP314; HNPCC8; TACSTD1; GA733-2; |
Gene ID : | 4072 |
mRNA Refseq : | NM_002354 |
Protein Refseq : | NP_002345 |
MIM : | 185535 |
UniProt ID : | P16422 |
Products Types
◆ Recombinant Protein | ||
EPCAM-1430H | Recombinant Human EPCAM Protein, His&GST-tagged | +Inquiry |
EPCAM-3368H | Recombinant Human EPCAM Protein, His/Flag/StrepII-tagged | +Inquiry |
EPCAM-3370H | Recombinant Human EPCAM Protein, GST-tagged | +Inquiry |
EPCAM-59H | Recombinant Human EPCAM Protein, His (Fc)-Avi-tagged | +Inquiry |
EPCAM-222H | Recombinant Human EPCAM Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
EPCAM-2143MCL | Recombinant Mouse EPCAM cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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