EPCAM

  • Official Full Name

    epithelial cell adhesion molecule

  • Overview

    This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
  • Synonyms

    EPCAM; epithelial cell adhesion molecule; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; antigen identified by monoclonal antibody AUA1; tumor-associated calcium signal transducer 1; 17-1A; 323/A3; CD326; CO-17A; EGP34; EGP40; GA733-2; HEA125; Ly74; MH99; MOC31; TACST-1; Adenocarcinoma-associated antigen; Cell surface glycoprotein Trop-1; Epithelial cell surface antigen; Epithelial glycoprotein; Epithelial glycoprotein 314; KS 1/4 antigen; Major gastrointestinal tumor-associated protein GA733-2; TACSTD1; human epithelial glycoprotein-2; Ep-CAM; membrane component, chromosome 4, surface marker (35kD glycoprotein); EGP; M1S2; CD326 antigen; Hegp314; ACSTD1; Adecatumumab; 503605-66-1; Citatuzumab bogatox; 945228-49-9; Citatuzumab bogatox; 945228-49-9; Tucotuzumab celmoleukin; 339986-90-2; Solitomab; 503605-66-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Chromatography Reagents
  • GMP Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Monkey
  • Mouse
  • Pig
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus macaque
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293 cells
  • HEK293T
  • Human Cell
  • Human cells
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian cell
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • Wheat Germ
  • Avi|Fc
  • Avi|His
  • C
  • 6×His
  • His
  • Avi
  • DDDDK
  • DDK
  • Fc
  • Flag
  • GST
  • hFc
  • HIgG1 Fc
  • His (Fc)
  • His(C
  • ter)
  • His\Avi
  • His|Flag|StrepII
  • His|T7
  • SUMO
  • mFc
  • Myc
  • N/A
  • N
  • Strep
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EPCAM-257H Active Recombinant Human EPCAM protein, His-tagged HEK293 His
Human EPCAM-571H Active Recombinant Human EPCAM, Fc-tagged, Biotinylated Human Cell Fc
Human EPCAM-475H Active Recombinant Human EPCAM protein, Fc-tagged Mammalian cells Fc Gln24 - Lys265
Human EPCAM-475HAF555 Active Recombinant Human EPCAM Protein, Fc-tagged, Alexa Fluor 555 conjugated Mammalian cells Fc Gln24-Lys265
Human EPCAM-475HAF488 Active Recombinant Human EPCAM Protein, Fc-tagged, Alexa Fluor 488 conjugated Mammalian cells Fc Gln24-Lys265
Human EPCAM-051H Active Recombinant Human EPCAM protein, Fc/Avi-tagged, Biotinylated HEK293 cells Fc/Avi Gln24-Lys265
Human EPCAM-475HAF647 Active Recombinant Human EPCAM Protein, Fc-tagged, Alexa Fluor 647 conjugated Mammalian cells Fc Gln24-Lys265
Human EPCAM-475HF Active Recombinant Human EPCAM Protein, Fc-tagged, FITC conjugated Mammalian cells Fc Gln24-Lys265
Human EPCAM-81H Recombinant Human EPCAM, Fc tagged HEK293 Fc Met1-Lys265
Human EPCAM-72H Recombinant Human EPCAM protein, His-tagged Insect Cell His
Human EPCAM-276H BiotinylatedRecombinant Human EPCAM protein(Met1-Lys265), His-tagged HEK293 C-His Met1-Lys265
Human EPCAM-7063H Recombinant Human EPCAM, His-tagged E.coli His 24-265aa
Human EPCAM-195H Active Recombinant Human EPCAM protein, His-tagged HEK293 His Met1-Lys265
Human EPCAM-289H Recombinant Human EPCAM Protein, DDK-tagged Sf9 Insect Cell DDK
Human EPCAM-77H Recombinant Human EPCAM protein E.coli N/A
Human EPCAM-7817H Recombinant Human EPCAM protein, Avi & His-tagged HEK293 Avi/His Gln 24 - Lys 265
Human EPCAM-3367H Recombinant Human EPCAM Protein Wheat Germ N/A
Human EPCAM-3368H Recombinant Human EPCAM Protein, His/Flag/StrepII-tagged Human cells His/Flag/StrepII
Human EPCAM-3370H Recombinant Human EPCAM Protein, GST-tagged Wheat Germ GST
Human EPCAM-2525HCL Recombinant Human EPCAM cell lysate Human Cell N/A
Human EPCAM-475HP Recombinant Human EPCAM protein, Fc-tagged, R-PE labeled Mammalian cells Fc
Human EPCAM-572H Recombinant Human EPCAM protein, Fc-Avi-tagged, Biotinylated HEK293 Fc-Avi Gln24-Lys265
Human EPCAM-195HAF647 Recombinant Human EPCAM Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His 253
Human EPCAM-7818H Recombinant Human EPCAM Protein, Fc-Avi-tagged, Biotinylated HEK293 Avi/Fc
Human EPCAM-81HP Recombinant Human EPCAM protein, Fc-tagged, R-PE labeled HEK293 Fc
Human EPCAM-475HA Recombinant Human EPCAM protein, Fc-tagged, APC labeled Mammalian cells Fc
Human EPCAM-81HA Recombinant Human EPCAM protein, Fc-tagged, APC labeled HEK293 Fc
Human EPCAM-785HF Recombinant Human EPCAM protein, His-tagged, FITC-Labeled HEK293 His Gln24-Lys265
Human EPCAM-349H Recombinant Human EPCAM Protein, Strep-tagged HEK293 Strep Gln 24 - Lys 265
Human EPCAM-195HAF555 Recombinant Human EPCAM Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His 253
Human EPCAM-350H Recombinant Human EpCAM protein(Met1-Lys265), His-Avi-tagged, Biotinylated HEK293 C-His-Avi Met1-Lys265
Human EPCAM-786HF Recombinant Human EpCAM protein, Fc-tagged, FITC-Labeled HEK293 Fc Gln24-Lys265
Human EPCAM-418H Recombinant Human EPCAM Protein (Met1-Lys265), HIgG1 Fc-tagged, Biotinylated Insect Cell HIgG1 Fc Met1-Lys265
Human EPCAM-151H Recombinant Human EPCAM Protein, His-tagged Human cells His
Human EPCAM-787H Recombinant Human EpCAM protein, mFc-tagged HEK293 mFc Gln24-Lys265
Human EPCAM-81HAF488 Recombinant Human EPCAM Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 480
Human EPCAM-195HAF488 Recombinant Human EPCAM Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His 253
Human EPCAM-2855H Recombinant Human EPCAM protein, His-SUMO-tagged E.coli His-SUMO 24-265aa
Human EpCAM-016M EPCAM-coupled magnetic beads
Human EPCAM-207H Recombinant Human EPCAM Protein, His\Avi-tagged Human Cell His\Avi
Human EPCAM-81HAF555 Recombinant Human EPCAM Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 480
Human EPCAM-195HF Recombinant Human EPCAM Protein, His-tagged, FITC conjugated HEK293 His 253
Human EPCAM-186HG Active GMP Recombinant Human EPCAM protein HEK293 DNA sequence encoding Human EpCAM(NCBI Reference Sequence: NP_002345.2) was expressed with His tag at the C-terminal.
Human EPCAM-59H Recombinant Human EPCAM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human EPCAM-81HF Recombinant Human EPCAM Protein, Fc-tagged, FITC conjugated HEK293 Fc 480
Human EPCAM-1430H Recombinant Human EPCAM Protein, His&GST-tagged E.coli N-His&GST Gln24-Leu264
Human EPCAM-66H Recombinant Active Human EPCAM Protein, His-tagged(C-ter) E.coli His(C-ter)
Human EPCAM-215H Active Recombinant Human EPCAM Protein (Gln24-Lys265), C-His tagged, Animal-free, Carrier-free E.coli C-His Gln24-Lys265
Human EPCAM-4309HF Recombinant Full Length Human EPCAM Protein In Vitro Cell Free System 886 amino acids
Human EPCAM-1391HFL Recombinant Full Length Human EPCAM Protein, C-Flag-tagged Mammalian cells Flag
Human EPCAM-219H Recombinant Human EPCAM Protein, Fc-tagged, Biotinylated HEK293 Fc 314
Human EPCAM-077H Recombinant Human EPCAM Protein, GLN24-LYS265, ECD, Tag Free, Biotinylated HEK293 Tag Free GLN24-LYS265, ECD
Human EPCAM-4310HF Recombinant Full Length Human EPCAM Protein, GST-tagged In Vitro Cell Free System GST 314 amino acids
Human EPCAM-220H Recombinant Human EPCAM Protein, His-tagged, Biotinylated HEK293 His 314
Human EPCAM-221H Recombinant Human EPCAM Protein, His-tagged HEK293 His 314
Human EPCAM-078H Recombinant Human EPCAM Protein, Gln24-Lys245, C-His-Avi tagged, Biotinylated HEK293 C-His-Avi Gln24-Lys245
Human EPCAM-097H Recombinant Human EPCAM Protein, His-tagged E.coli His
Human EPCAM-222H Recombinant Human EPCAM Protein, Fc-tagged HEK293 Fc 314
Human EPCAM-3152H Recombinant Human EPCAM Protein (Gln24-Lys265), His tagged E.coli His Gln24-Lys265
Human EpCAM-1399H Recombinant Human EpCAM protein, Fc-tagged, Biotinylated HEK293 Fc Gln24-Lys265
Human EPCAM-81HAF647 Recombinant Human EPCAM Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 480
Human EPCAM-285H Recombinant Human EPCAM Protein (Gln24-Gly314), C-6×His-tagged HEK293 C-6×His Gln24-Gly314
Human EPCAM-4480H Recombinant Human EPCAM Protein (Met1-Lys265), C-His tagged Mammalian cells C-His Met1-Lys265
Human EPCAM-2666H Recombinant Human EPCAM protein(161-250 aa), C-His-tagged E.coli C-His 161-250 aa
Human EPCAM-223H Recombinant Human EPCAM Protein, Strep-tagged HEK293 Strep 314
Human EPCAM-59H-B Recombinant Human EPCAM Protein Pre-coupled Magnetic Beads HEK293
Human EPCAM-2571M Whole Blood EPCAM protein-coupled magnetic MicroBeads
Mouse Epcam-191M Active Recombinant Mouse Epcam protein, Fc-tagged Mammalian cells Fc
Mouse Epcam-191MF Active Recombinant Mouse Epcam Protein, Fc-tagged, FITC conjugated Mammalian cells Fc
Mouse Epcam-191MAF488 Active Recombinant Mouse Epcam Protein, Fc-tagged, Alexa Fluor 488 conjugated Mammalian cells Fc
Mouse Epcam-191MAF647 Active Recombinant Mouse Epcam Protein, Fc-tagged, Alexa Fluor 647 conjugated Mammalian cells Fc
Mouse Epcam-191MAF555 Active Recombinant Mouse Epcam Protein, Fc-tagged, Alexa Fluor 555 conjugated Mammalian cells Fc
Mouse Epcam-283M Recombinant Mouse Epcam protein, His-tagged HEK293 His Gln24-Thr266
Mouse EPCAM-2143MCL Recombinant Mouse EPCAM cell lysate Human Cell N/A
Mouse Epcam-4234M Recombinant Mouse Epcam protein, His-tagged Mammalian cell His 24-266aa
Mouse Epcam-31M Recombinant Mouse Epcam Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Epcam-191MA Recombinant Mouse Epcam protein, Fc-tagged, APC labeled Mammalian cells Fc
Mouse Epcam-283MF Recombinant Mouse Epcam Protein, His-tagged, FITC conjugated HEK293 His Gln24-Thr266
Mouse Epcam-283MAF647 Recombinant Mouse Epcam Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His Gln24-Thr266
Mouse Epcam-4235M Recombinant Mouse Epcam protein E.coli N/A 24-266aa
Mouse Epcam-31M-B Recombinant Mouse Epcam Protein Pre-coupled Magnetic Beads HEK293
Mouse Epcam-283MAF555 Recombinant Mouse Epcam Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His Gln24-Thr266
Mouse Epcam-283MAF488 Recombinant Mouse Epcam Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His Gln24-Thr266
Mouse Epcam-2842M Recombinant Mouse Epcam Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse EpCAM-224M Recombinant Mouse EpCAM Protein, His-tagged HEK293 His 315
Mouse Epcam-191MP Recombinant Mouse Epcam protein, Fc-tagged, R-PE labeled Mammalian cells Fc
Rat Epcam-7481R Recombinant Rat Epcam protein, hFc-tagged HEK293 hFc Met1-Thr266
Rat Epcam-7482R Recombinant Rat Epcam protein(Met1-Thr266), His-tagged HEK293 C-His Met1-Thr266
Rat EPCAM-2118R Recombinant Rat EPCAM Protein Mammalian Cell His
Rat EPCAM-1434RCL Recombinant Rat EPCAM cell lysate Human Cell N/A
Rat EPCAM-1775R Recombinant Rat EPCAM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Epcam-7481RP Recombinant Rat Epcam protein, Fc-tagged, R-PE labeled HEK293 Fc
Rat Epcam-7482RAF488 Recombinant Rat Epcam Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His 254
Rat Epcam-7481RA Recombinant Rat Epcam protein, Fc-tagged, APC labeled HEK293 Fc
Rat Epcam-7481RAF488 Recombinant Rat Epcam Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 484
Rat Epcam-7481RF Recombinant Rat Epcam Protein, Fc-tagged, FITC conjugated HEK293 Fc 484
Rat Epcam-7482RF Recombinant Rat Epcam Protein, His-tagged, FITC conjugated HEK293 His 254
Rat EPCAM-1775R-B Recombinant Rat EPCAM Protein Pre-coupled Magnetic Beads HEK293
Rat Epcam-7481RAF647 Recombinant Rat Epcam Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 484
Rat Epcam-7482RAF647 Recombinant Rat Epcam Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His 254
Rat Epcam-7481RAF555 Recombinant Rat Epcam Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 484
Rat Epcam-7482RAF555 Recombinant Rat Epcam Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His 254
Monkey EPCAM-185CF Recombinant Cynomolgus EPCAM Protein, DDDDK-tagged, FITC conjugated HEK293 DDDDK Met1-Lys265, 248
Monkey EPCAM-202CAF555 Recombinant Monkey EPCAM Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His Gln24-Lys265
Monkey EPCAM-202CAF647 Recombinant Monkey EPCAM Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His Gln24-Lys265
Monkey EPCAM-202CAF488 Recombinant Monkey EPCAM Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His Gln24-Lys265
Monkey EPCAM-186CF Recombinant Monkey EPCAM Protein, Fc-tagged, FITC conjugated HEK293 Fc Met1-Lys265, 480
Monkey EPCAM-185CAF488 Recombinant Cynomolgus EPCAM Protein, DDDDK-tagged, Alexa Fluor 488 conjugated HEK293 DDDDK Met1-Lys265, 248
Monkey EPCAM-185CAF647 Recombinant Cynomolgus EPCAM Protein, DDDDK-tagged, Alexa Fluor 647 conjugated HEK293 DDDDK Met1-Lys265, 248
Monkey EPCAM-186CAF488 Recombinant Monkey EPCAM Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc Met1-Lys265, 480
Monkey EPCAM-186CAF647 Recombinant Monkey EPCAM Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc Met1-Lys265, 480
Monkey EPCAM-202CF Recombinant Monkey EPCAM Protein, His-tagged, FITC conjugated HEK293 His Gln24-Lys265
Monkey EPCAM-185CAF555 Recombinant Cynomolgus EPCAM Protein, DDDDK-tagged, Alexa Fluor 555 conjugated HEK293 DDDDK Met1-Lys265, 248
Monkey EPCAM-186CAF555 Recombinant Monkey EPCAM Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc Met1-Lys265, 480
Cynomolgus EPCAM-186CA Recombinant Cynomolgus EPCAM protein, Fc-tagged, APC labeled HEK293 Fc
Cynomolgus EPCAM-186CP Recombinant Cynomolgus EPCAM protein, Fc-tagged, R-PE labeled HEK293 Fc
Cynomolgus EPCAM-1821C Recombinant Cynomolgus EPCAM Protein, His-tagged HEK293 His Met1-Lys265
Cynomolgus Monkey EPCAM-186C Recombinant Cynomolgus EPCAM, Fc-tagged Human Cell Fc Met1-Lys265
Cynomolgus Monkey EPCAM-185C Recombinant Cynomolgus EPCAM Human Cell N/A Met1-Lys265
Cynomolgus Monkey EPCAM-001CCL Recombinant Cynomolgus EPCAM cell lysate Human Cell N/A
Homo sapiens (Human) RFL13291HF Recombinant Full Length Human Epithelial Cell Adhesion Molecule(Epcam) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (24-314)
Homo sapiens (Human) RFL5563HF Recombinant Full Length Human Epithelial Cell Adhesion Molecule(Epcam) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (24-314)
Rattus norvegicus (Rat) RFL3774RF Recombinant Full Length Rat Epithelial Cell Adhesion Molecule(Epcam) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (24-315)
Rhesus Macaque EPCAM-1482R Recombinant Rhesus monkey EPCAM Protein, His-tagged Mammalian Cell His
Rhesus macaque EPCAM-202C Recombinant Rhesus macaque EPCAM protein, His-tagged HEK293 His Gln24-Lys265
Rhesus Macaque EPCAM-1307R-B Recombinant Rhesus Macaque EPCAM Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque EPCAM-1307R Recombinant Rhesus Macaque EPCAM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus macaque EpCAM-225R Recombinant Rhesus macaque EpCAM Protein, His-tagged HEK293 His 314
Zebrafish EPCAM-2369Z Recombinant Zebrafish EPCAM Mammalian Cell His
Pig EPCAM-6766P Recombinant Pig EPCAM protein, His & T7-tagged E.coli His/T7 Gln25~Gln265 (Accession # Q75QW1) linked with LEHHHHHH
Chicken EPCAM-1936C Recombinant Chicken EPCAM Mammalian Cell His
Chicken EPCAM-6765C Recombinant Chicken EPCAM protein, His-tagged E.coli His Asp21~Gly260 linked with LEHHHHHH
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

EPCAM involved in several pathways and played different roles in them. We selected most pathways EPCAM participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with EPCAM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

EPCAM has several biochemical functions, for example, cadherin binding involved in cell-cell adhesion, protein binding, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPCAM itself. We selected most functions EPCAM had, and list some proteins which have the same functions with EPCAM. You can find most of the proteins on our site.

Function Related Protein
cadherin binding involved in cell-cell adhesion
protein bindingNUAK1;PDE4C;PRKCZ;CLN3;LDLR;EPB49;LRPAP1;S100A11;RAB34
protein complex bindingATF1;RIPK3;SIX2;AP2B1;SLC25A3;ST13;UQCRC2;KRIT1;PPP2R2A

EPCAM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPCAM here. Most of them are supplied by our site. Hope this information will be useful for your research of EPCAM.

CFTR

Research Area

Related articles

Hyun, KA; Lee, TY; et al. Two-stage microfluidic chip for selective isolation of circulating tumor cells (CTCs). BIOSENSORS & BIOELECTRONICS 67:86-92(2015).
Gu, YJ; Ju, C; et al. Detection of circulating tumor cells in prostate cancer based on carboxylated graphene oxide modified light addressable potentiometric sensor. BIOSENSORS & BIOELECTRONICS 66:24-31(2015).
  • Q&As
  • Reviews

Q&As (7)

Ask a question
In which types of tissues is EpCAM predominantly expressed? 12/07/2022

EpCAM is highly expressed in epithelial tissues and some cancer cells.

How does EpCAM contribute to cell adhesion? 08/21/2022

It has a controversial role in cell adhesion, possibly contributing to both cell-cell adhesion and anti-adhesive properties.

What is the primary function of EpCAM in cells? 04/16/2022

EpCAM primarily functions in cell signaling, proliferation, and migration.

What role does EpCAM play in cancer progression? 03/19/2022

It often has a pro-tumorigenic role, promoting cancer cell proliferation, migration, and invasion.

How is EpCAM used as a biomarker in cancer diagnosis? 03/28/2021

EpCAM is used as a biomarker to detect and isolate circulating tumor cells.

What therapeutic strategies are being explored involving EpCAM? 11/23/2018

Strategies include developing EpCAM-targeted therapies for cancer treatment.

Are there known genetic alterations in EpCAM associated with specific health conditions? 11/07/2018

Genetic alterations in EpCAM are linked to some hereditary cancer syndromes.

Customer Reviews (3)

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Reviews
02/13/2022

    Reliable for assays, satisfied customer.

    09/09/2019

      High-quality product, consistent results.

      04/03/2019

        Quick delivery, product as described.

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