Active Recombinant Full Length Human MAP2K1 Protein, GST-tagged
Cat.No. : | MAP2K1-2354HF |
Product Overview : | Full-length human MAP2K1 [1-393(end) amino acids and F129L of accession number NP_002746.1] was co-expressed as N-terminal GST-fusion protein (70 kDa) with human His-tagged RAF1 [306-648(end) amino acids and Y340D and Y341D of accession number NP_002871.1] using baculovirus expression system. GST-MAP2K1[F129L] was purified by using glutathione sepharose chromatography and Ni-NTA affinity chromatography. |
- Specification
- Gene Information
- Related Products
Source : | Insect (sf21) |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5 |
Bio-activity : | The activity was determined by ELISA. The enzyme was incubated with GST-fused substrate protein, and after stopping kinase reaction by EDTA, the reaction solution was transferred into glutathione-coated plate. Phosphorylation was detected by anti-phospho antibody and HRP-labeled anti-rabbit IgG(or HRP-labeled anti-mouse IgG) . |
Protein length : | 1-393(end) |
Purity : | 99% |
Applications : | SDS-PAGE |
Storage : | Store at -80C. Avoid repeating freeze-thaws. |
Gene Name : | mitogen-activated protein kinase kinase 1 |
Official Symbol : | MAP2K1 |
Synonyms : | MAP2K1;CFC3;MAPKK1;MEK1;MKK1;PRKMK1 |
Protein Refseq : | NP_002746.1 |
UniProt ID : | Q02750 |
Products Types
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◆ Lysates | ||
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◆ Assay kits | ||
Kit-1614 | MEK1 Kinase Binding Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, there are clinical trials exploring the efficacy and safety of MAP2K1 inhibitors in various cancers and other diseases.
Some diagnostic tests may analyze MAP2K1 mutations, especially in the context of cancer, to inform treatment decisions.
MAP2K1 mutations can serve as biomarkers in cancer diagnostics, aiding in the identification and classification of tumors.
MAP2K1 mutations can be associated with resistance to certain cancer therapies, making it important to understand its role in treatment response.
Yes, MAP2K1 inhibitors are being explored as targeted therapies in cancer treatment, aiming to block the abnormal signaling associated with MAP2K1 mutations.
Customer Reviews (3)
Write a reviewThe unmatched performance of the MAP2K1 protein in both ELISA assays and protein electron microscopy structure analysis showcases its versatility and reliability in various experimental settings.
The MAP2K1 protein finds extensive utility in protein electron microscopy structure analysis.
With its exceptional specificity and sensitivity, it enables precise and reliable detection of target molecules, making it a valuable tool in the field of diagnostic and research applications.
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