Recombinant Full Length Human PPT1 Protein

• Cat.No.: PPT1-393HF
• Product Overview: Recombinant full length Human PPT1 protein with an N terminal proprietary tag; Predicted MW 59.73 kDa.

Specification

• Description: The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 59.730kDa inclusive of tags
• Protein Length: 306 amino acids
• AA Sequence: MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHG MGDSCCNPLSMGAIKKMVEKKIPGIYVLSLEIGKTLMEDV ENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQGGQF LRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHIC DFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSI FLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVD SEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQL VFLATEGDHLQLSEEWFYAHIIPFLG
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: PPT1 palmitoyl-protein thioesterase 1 [ Homo sapiens ]
• Official Symbol: PPT1
• Synonyms: PPT1; palmitoyl-protein thioesterase 1; PPT; ceroid lipofuscinosis; neuronal 1; infantile; CLN1; INCL
• Gene ID: 5538
• mRNA Refseq: NM_000310
• Protein Refseq: NP_000301
• MIM: 600722
• UniProt ID: P50897