Recombinant Human ABCC4 Protein (M1-L1325), eGFP, Strep II, 10×His tagged
Cat.No. : | ABCC4-0104H |
Product Overview : | Recombinant Human ABCC4(M1-L1325 end) (E1202Q)-3C-eGFP-Strep II-10His Protein was expressed in Mammalian cell. |
- Specification
- Gene Information
- Related Products
Description : | ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds and xenobiotics from cells. Transports a range of endogenous molecules that have a key role in cellular communication and signaling, including cyclic nucleotides such as cyclic AMP (cAMP) and cyclic GMP (cGMP), bile acids, steroid conjugates, urate, and prostaglandins. Mediates the ATP-dependent efflux of glutathione conjugates such as leukotriene C4 (LTC4) and leukotriene B4 (LTB4) too. The presence of GSH is necessary for the ATP-dependent transport of LTB4, whereas GSH is not required for the transport of LTC4. Mediates the cotransport of bile acids with reduced glutathione (GSH). Transports a wide range of drugs and their metabolites, including anticancer, antiviral and antibiotics molecules. Confers resistance to anticancer agents such as methotrexate. |
Source : | Mammalian cell |
Species : | Human |
Tag : | eGFP, Strep II,10His |
Form : | Liquid |
Protein Length : | M1-L1325 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 85% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | 50 mM Tris-HCl (pH 8.5), 150 mM KCl, 2 mM DTT, 2 mM MgCl2, 0.005% (w/v) GDN |
Shipping : | It is shipped out with blue ice. |
Gene Name : | ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 [ Homo sapiens (human) ] |
Official Symbol : | ABCC4 |
Synonyms : | ABCC4; ATP-binding cassette, sub-family C (CFTR/MRP), member 4; multidrug resistance-associated protein 4; bA464I2.1 (ATP binding cassette; sub family C (CFTR/MRP); member 4); canalicular multispecific organic anion transporter (ABC superfamily); EST170205; MOAT B; MOATB; MRP4; multidrug resistance associated protein 4; multispecific organic anion transporter B; MRP/cMOAT-related ABC transporter; ATP-binding cassette sub-family C member 4; multi-specific organic anion transporter B; bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); MOAT-B; |
Gene ID : | 10257 |
mRNA Refseq : | NM_001105515 |
Protein Refseq : | NP_001098985 |
MIM : | 605250 |
UniProt ID : | O15439 |
Products Types
◆ Recombinant Protein | ||
ABCC4-0103H | Recombinant Human ABCC4 Protein (M1-L1325), eGFP, Strep II, 10×His tagged | +Inquiry |
ABCC4-2515C | Recombinant Chicken ABCC4 | +Inquiry |
ABCC4-0492H | Recombinant Human ABCC4 Protein (Ile1041-Gln1274), N-His-tagged | +Inquiry |
ABCC4-048H | Recombinant Human ABCC4 Protein, GST-Tagged | +Inquiry |
ABCC4-1621Z | Recombinant Zebrafish ABCC4 | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket