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Recombinant Human ACVR1B Protein, Fc-tagged

Cat.No. : ACVR1B-082H
Product Overview : Recombinant human ACVR1B protein with Fc tag was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : Fc
Form : Lyophilized
Molecular Mass : 38 kDa
Protein Length : 505
AA Sequence : MAESAGASSFFPLVVLLLAGSGGSG PRGVQALLCACTSCLQANYTCETDG ACMVSIFNLDGMEHHVRTCIPKVEL VPAGKPFYCLSSEDLRNTHCCYTDY CNRIDLRVPSGHLKEPEHPSMWGPV ELVGIIAGPVFLLFLIIIIVFLVIN YHQRVYHNRQRLDMEDPSCEMCLSK DKTLQDLVYDLSTSGSGSGLPLFVQ RTVARTIVLQEIIGKGRFGEVWRGR WRGGDVAVKIFSSREERSWFREAEI YQTVMLRHENILGFIAADNKDNGTW TQLWLVSDYHEHGSLFDYLNRYTVT IEGMIKLALSAASGLAHLHMEIVGT QGKPGIAHRDLKSKNILVKKNGMCA IADLGLAVRHDAVTDTIDIAPNQRV GTKRYMAPEVLDETINMKHFDSFKC ADIYALGLVYWEIARRCNSGGVHEE YQLPYYDLVPSDPSIEEMRKVVCDQ KLRPNIPNWWQSYEALRVMGKMMRE CWYANGAARLTALRIKKTLSQLSVQ EDVKI
Purity : > 98%
Applications : WB; ELISA; FACS; FC
Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
Storage : At -20 centigrade.
Concentration : 1 mg/mL
Storage Buffer : PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
Gene Name : ACVR1B activin A receptor, type IB [ Homo sapiens (human) ]
Official Symbol : ACVR1B
Synonyms : ACVR1B; activin A receptor, type IB; ACVRLK4; activin receptor type-1B; ActRIB; ALK4; SKR2; activin receptor-like kinase 4; activin A receptor, type II-like kinase 4; serine/threonine-protein kinase receptor R2; ACTRIB;
Gene ID : 91
mRNA Refseq : NM_004302
Protein Refseq : NP_004293
MIM : 601300
UniProt ID : P36896

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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