| Description : |
This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. This gene is predominantly expressed in the testis. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease, disintegrin and epidermal growth factor-like domains. This gene is located in a cluster of other disintegrin and metallopeptidase family genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
87.9 kDa |
| AA Sequence : |
MFRLWLLLAGLCGLLASRPGFQNSL LQIVIPEKIQTNTNDSSEIEYEQIS YIIPIDEKLYTVHLKQRYFLADNFM IYLYNQGSMNTYSSDIQTQCYYQGN IEGYPDSMVTLSTCSGLRGILQFEN VSYGIEPLESAVEFQHVLYKLKNED NDIAIFIDRSLKEQPMDDNIFISEK SEPAVPDLFPLYLEMHIVVDKTLYD YWGSDSMIVTNKVIEIVGLANSMFT QFKVTIVLSSLELWSDENKISTVGE ADELLQKFLEWKQSYLNLRPHDIAY LLIYMDYPRYLGAVFPGTMCITRYS AGVALYPKEITLEAFAVIVTQMLAL SLGISYDDPKKCQCSESTCIMNPEV VQSNGVKTFSSCSLRSFQNFISNVG VKCLQNKPQMQKKSPKPVCGNGRLE GNEICDCGTEAQCGPASCCDFRTCV LKDGAKCYKGLCCKDCQILQSGVEC RPKAHPECDIAENCNGSSPECGPDI TLINGLSCKNNKFICYDGDCHDLDA RCESVFGKGSRNAPFACYEEIQSQS DRFGNCGRDRNNKYVFCGWRNLICG RLVCTYPTRKPFHQENGDVIYAFVR DSVCITVDYKLPRTVPDPLAVKNGS QCDIGRVCVNRECVESRIIKASAHV CSQQCSGHGVCDSRNKCHCSPGYKP PNCQIRSKGFSIFPEEDMGSIMERA SGKTENTWLLGFLIALPILIVTTAI VLARKQLKKWFAKEEEFPSSESKSE GSTQTYASQSSSEGSTQTYASQTRS ESSSQADTSKSKSEDSAEAYTSRSK SQDSTQTQSSSNTRTRPLEQKLISE EDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
