Recombinant Human ANTXR1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human ANTXR1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : ANTXR1-5916H
Product Overview : ANTXR1 MS Standard C13 and N15-labeled recombinant protein (NP_060623) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 37.1 kDa
AA Sequence : MATAERRALG IGFQWLSLAT LVLICAGQGG RREDGGPACY GGFDLYFILD KSGSVLHHWN EIYYFVEQLA HKFISPQLRM SFIVFSTRGT TLMKLTEDRE QIRQGLEELQ KVLPGGDTYM HEGFERASEQ IYYENRQGYR TASVIIALTD GELHEDLFFY SEREANRSRD LGAIVYCVGV KDFNETQLAR IADSKDHVFP VNDGFQALQG IIHSILKKSC IEILAAEPST ICAGESFQVV VRGNGFRHAR NVDRVLCSFK INDSVTLNEK PFSVEDTYLL CPAPILKEVG MKAALQVSMN DGLSFISSSV IITTTHCSLH KIASGPTTAA CMETRTRPLE QKLISEEDLA ANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : ANTXR1 anthrax toxin receptor 1 [ Homo sapiens (human) ]
Official Symbol : ANTXR1
Synonyms : ANTXR1; anthrax toxin receptor 1; anthrax toxin receptor; ATR; FLJ10601; FLJ21776; TEM8; tumor endothelial marker 8 precursor; 2310008J16Rik; 2810405N18Rik; tumor endothelial marker 8; FLJ11298;
Gene ID : 84168
mRNA Refseq : NM_018153
Protein Refseq : NP_060623
MIM : 606410
UniProt ID : Q9H6X2

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