Recombinant Human ANXA2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ANXA2-1086H
• Product Overview: ANXA2 MS Standard C13 and N15-labeled recombinant protein (NP_001002857) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 38.6 kDa
• AA Sequence: MSTVHEILCKLSLEGDHSTPPSAYG SVKAYTNFDAERDALNIETAIKTKG VDEVTIVNILTNRSNAQRQDIAFAY QRRTKKELASALKSALSGHLETVIL GLLKTPAQYDASELKASMKGLGTDE DSLIEIICSRTNQELQEINRVYKEM YKTDLEKDIISDTSGDFRKLMVALA KGRRAEDGSVIDYELIDQDARDLYD AGVKRKGTDVPKWISIMTERSVPHL QKVFDRYKSYSPYDMLESIRKEVKG DLENAFLNLVQCIQNKPLYFADRLY DSMKGKGTRDKVLIRIMASRSEVDM LKIRSEFKRKYGKSLYYYIQQDTKG DYQKALLYLCGGDDTRTRPLEQKLI SEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ANXA2 annexin A2 [ Homo sapiens (human) ]
• Official Symbol: ANXA2
• Synonyms: ANXA2; annexin A2; ANX2, ANX2L4, CAL1H, LPC2D; annexin II; LIP2; annexin-2; protein I; lipocortin II; chromobindin 8; chromobindin-8; calpactin I heavy chain; calpactin-1 heavy chain; calpactin I heavy polypeptide; placental anticoagulant protein IV; P36; ANX2; LPC2; CAL1H; LPC2D; ANX2L4; PAP-IV
• Gene ID: 302
• mRNA Refseq: NM_001002857
• Protein Refseq: NP_001002857
• MIM: 151740
• UniProt ID: P07355