Recombinant Human AOC3 protein, GST-tagged

• Cat.No.: AOC3-641H
• Product Overview: Human AOC3 full-length ORF ( AAH50549.1, 1 a.a. - 763 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 111 kDa
• AA Sequence: MNQKTILVLLILAVITIFALVCVLL VGRGGDGGEPSQLPHCPSVSPSAQP WTHPGQSQLFADLSREELTAVMRFL TQRLGPGLVDAAQARPSDNCVFSVE LQLPPKAAALAHLDRGSPPPAREAL AIVFFGRQPQPNVSELVVGPLPHPS YMRDVTVERHGGPLPYHRRPVLFQE YLDIDQMIFNRELPQASGLLHHCCF YKHRGRNLVTMTTAPRGLQSGDRAT WFGLYYNISGAGFFLHHVGLELLVN HKALDPARWTIQKVFYQGRYYDSLA QLEAQFEAGLVNVVLIPDNGTGGSW SLKSPVPPGPAPPLQFYPQGPRFSV QGSRVASSLWTFSFGLGAFSGPRIF DVRFQGERLVYEISLQEALAIYGGN SPAAMTTRYVDGGFGMGKYTTPLTR GVDCPYLATYVDWHFLLESQAPKTI RDAFCVFEQNQGLPLRRHHSDLYSH YFGGLAETVLVVRSMSTLLNYDYVW DTVFHPSGAIEIRFYATGYISSAFL FGATGKYGNQVSEHTLGTVHTHSAH FKVDLDVAGLENWVWAEDMVFVPMA VPWSPEHQLQRLQVTRKLLEMEEQA AFLVGSATPRYLYLASNHSNKWGHP RGYRIQMLSFAGEPLPQNSSMARGF SWERYQLAVTQRKEEEPSSSSVFNQ NDPWAPTVDFSDFINNETIAGKDLV AWVTAGFLHIPHAEDIPNTVTVGNG VGFFLRPYNFFDEDPSFYSADSIYF RGDQDAGACEVNPLACLPQAAACAP DLPAFSHGGFSHN
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AOC3 amine oxidase, copper containing 3 (vascular adhesion protein 1) [ Homo sapiens ]
• Official Symbol: AOC3
• Synonyms: AOC3; amine oxidase, copper containing 3 (vascular adhesion protein 1); membrane primary amine oxidase; HPAO; VAP 1; VAP1; copper amine oxidase; vascular adhesion protein 1; semicarbazide-sensitive amine oxidase; SSAO; VAP-1
• Gene ID: 8639
• mRNA Refseq: NM_003734
• Protein Refseq: NP_003725
• MIM: 603735
• UniProt ID: Q16853