| Description : |
This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Form : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Molecular Mass : |
149.6 kDa |
| AA Sequence : |
MEPNDSTSTAVEEPDSLEVLVKTLD SQTRTFIVGAQMNVKEFKEHIAASV SIPSEKQRLIYQGRVLQDDKKLQEY NVGGKVIHLVERAPPQTHLPSGASS GTGSASATHGGGSPPGTRGPGASVH DRNANSYVMVGTFNLPSDGSAVDVH INMEQAPIQSEPRVRLVMAQHMIRD IQTLLSRMECRGGPQPQHSQPPPQP PAVTPEPVALSSQTSEPVESEAPPR EPMEAEEVEERAPAQNPELTPGPAP AGPTPAPETNAPNHPSPAEYVEVLQ ELQRLESRLQPFLQRYYEVLGAAAT TDYNNNHEGREEDQRLINLVGESLR LLGNTFVALSDLRCNLACTPPRHLH VVRPMSHYTTPMVLQQAAIPIQINV GTTVTMTGNGTRPPPTPNAEAPPPG PGQASSVAPSSTNVESSAEGAPPPG PAPPPATSHPRVIRISHQSVEPVVM MHMNIQDSGTQPGGVPSAPTGPLGP PGHGQTLGQQVPGFPTAPTRVVIAR PTPPQARPSHPGGPPVSGTLQGAGL GTNASLAQMVSGLVGQLLMQPVLVA QGTPGMAPPPAPATASASAGTTNTA TTAGPAPGGPAQPPPTPQPSMADLQ FSQLLGNLLGPAGPGAGGSGVASPT ITVAMPGVPAFLQGMTDFLQATQTA PPPPPPPPPPPPAPEQQTMPPPGSP SGGAGSPGGLGLESLSPEFFTSVVQ GVLSSLLGSLGARAGSSESIAAFIQ RLSGSSNIFEPGADGALGFFGALLS LLCQNFSMVDVVMLLHGHFQPLQRL QPQLRSFFHQHYLGGQEPTPSNIRM ATHTLITGLEEYVRESFSLVQVQPG VDIIRTNLEFLQEQFNSIAAHVLHC TDSGFGARLLELCNQGLFECLALNL HCLGGQQMELAAVINGRIRRMSRGV NPSLVSWLTTMMGLRLQVVLEHMPV GPDAILRYVRRVGDPPQPLPEEPME VQGAERASPEPQRENASPAPGTTAE EAMSRGPPPAPEGGSRDEQDGASAE TEPWAAAVPPEWVPIIQQDIQSQRK VKPQPPLSDAYLSGMPAKRRKTMQG EGPQLLLSEAVSRAAKAAGARPLTS PESLSRDLEAPEVQESYRQQLRSDI QKRLQEDPNYSPQRFPNAQRAFADD P |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
