Active Recombinant Human CAMK2D Protein, GST-Tagged

• Cat.No.: CAMK2D-0331H
• Product Overview: Human CAMK2D (NP_742113.1, 1 a.a. - 478 a.a.) full-length recombinant protein with GST tag expressed in baculovirus infected Sf21 cells. cells.

Specification

• Description: The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.[provided by RefSeq, Nov 2008]
• Source: Insect Cell
• Species: Human
• Tag: GST
• Form: Liquid
• Bio-activity: The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate, Mg(or Mn)/ATP, and Ca/Calmodulin. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip TM3000. Substrate: GS peptide. ATP: 100 μM.
• Molecular Mass: 81 kDa
• Purity: 82 % by SDS-PAGE/CBB staining
• Applications: Functional Study
  SDS-PAGE
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol)

Gene Information

• Gene Name: CAMK2D calcium/calmodulin-dependent protein kinase II delta [ Homo sapiens ]
• Official Symbol: CAMK2D
• Synonyms: CAMK2D; calcium/calmodulin-dependent protein kinase II delta; calcium/calmodulin dependent protein kinase (CaM kinase) II delta, CAMKD; calcium/calmodulin-dependent protein kinase type II subunit delta; CaMK-II delta subunit; caMK-II subunit delta; CaM-kinase II delta chain; CaM kinase II delta subunit; caM kinase II subunit delta; calcium/calmodulin-dependent protein kinase type II delta chain; calcium/calmodulin-dependent protein kinase (CaM kinase) II delta; CAMKD; MGC44911; DKFZp686I2288; DKFZp686G23119
• Gene ID: 817
• mRNA Refseq: NM_001221
• Protein Refseq: NP_001212
• MIM: 607708
• UniProt ID: Q13557