Recombinant Human CDH11 Protein, His-Flag-StrepII-Tagged

• Cat.No.: CDH11-0971H
• Product Overview: Purified CDH11 (NP_001788.2 54 a.a. - 617 a.a.) human recombinant protein with His-Flag-StrepII tag at N-terminus expressed in human cells.

Specification

• Description: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]
• Source: Human cells
• Species: Human
• Tag: His-Flag-StrepII
• Form: Liquid
• Bio-activity: Not Tested
• Molecular Mass: 67.32 kDa
• AA Sequence: GWVWNQFFVIEEYTGPDPVLVGRLH SDIDSGDGNIKYILSGEGAGTIFVI DDKSGNIHATKTLDREERAQYTLMA QAVDRDTNRPLEPPSEFIVKVQDIN DNPPEFLHETYHANVPERSNVGTSV IQVTASDADDPTYGNSAKLVYSILE GQPYFSVEAQTGIIRTALPNMDREA KEEYHVVIQAKDMGGHMGGLSGTTK VTITLTDVNDNPPKFPQSVYQMSVS EAAVPGEEVGRVKAKDPDIGENGLV TYNIVDGDGMESFEITTDYETQEGV IKLKKPVDFETKRAYSLKVEAANVH IDPKFISNGPFKDTVTVKISVEDAD EPPMFLAPSYIHEVQENAAAGTVVG RVHAKDPDAANSPIRYSIDRHTDLD RFFTINPEDGFIKTTKPLDREETAW LNITVFAAEIHNRHQEAKVPVAIRV LDVNDNAPKFAAPYEGFICESDQTK PLSNQPIVTISADDKDDTANGPRFI FSLPPEIIHNPNFTVRDNRDNTAGV YARRGGFSRQKQDLYLLPIVISDGG IPPMSSTNTLTIKVCGCDVNGALLS CNAEAYILNAGLST
• Applications: Western Blot
  Enzyme-linked Immunoabsorbent Assay
  SDS-PAGE
  Protein Interaction
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Concentration: ≥ 10 μg/mL
• Storage Buffer: 100 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, and 5 mM desthiobiotin.

Gene Information

• Gene Name: CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) [ Homo sapiens ]
• Official Symbol: CDH11
• Synonyms: CDH11; cadherin 11, type 2, OB-cadherin (osteoblast); cadherin-11; CAD11; OB; OB Cadherin; CDHOB; OSF-4
• Gene ID: 1009
• mRNA Refseq: NM_001797
• Protein Refseq: NP_001788
• MIM: 600023
• UniProt ID: P55287