Recombinant Human CSTA, His-tagged

• Cat.No.: CSTA-27200TH
• Product Overview: Recombinant full length Human Cystatin A with an N terminal His tag; 118 amino acids with a predicted MWt 13.1kDa including tag.

Specification

• Description: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.
• Protein length: 98 amino acids
• Conjugation: HIS
• Molecular Weight: 13.100kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MIPGGLSEAKPATPEIQEIV DKVKPQLEEK TNETYGKLEA VQYKTQVVAGTNYYIKVRAG DNKYMHLKVF KSLPGQNEDL VLTGYQVDKNKDDELTGF
• Sequence Similarities: Belongs to the cystatin family.

Gene Information

• Gene Name: CSTA cystatin A (stefin A) [ Homo sapiens ]
• Official Symbol: CSTA
• Synonyms: CSTA; cystatin A (stefin A); STF1, STFA; cystatin-A
• Gene ID: 1475
• mRNA Refseq: NM_005213
• Protein Refseq: NP_005204
• MIM: 184600
• Uniprot ID: P01040
• Chromosome Location: 3q21
• Function: cysteine-type endopeptidase inhibitor activity; protease binding; protein binding, bridging; structural molecule activity