Recombinant Human DAO Protein, GST-tagged

• Cat.No.: DAO-2330H
• Product Overview: Human DAO full-length ORF (BAG35832.1, 1 a.a. - 347 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 65.9 kDa
• AA Sequence: MRVVVIGAGVIGLSTALCIHERYHS VLQPLDIKVYADRFTPLTTTDVAAG LWQPYLSDPNNPQEADWSQQTFDYL LSHVHSPNAENLGLFLISGYNLFHE AIPDPSWKDTVLGFRKLTPRELDMF PDYGYGWFHTSLILEGKNYLQWLTE RLTERGVKFFQRKVESFEEVAREGA DVIVNCTGVWAGALQRDPLLQPGRG QIMKVDAPWMKHFILTHDPERGIYN SPYIIPGTQTVTLGGIFQLGNWSEL NNIQDHNTIWEGCCRLEPTLKNARI IGERTGFRPVRPQIRLEREQLRTGP SNTEVIHNYGHGGYGLTIHWGCALE AAKLFGRILEEKKLSRMPPSHL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DAO D-amino-acid oxidase [ Homo sapiens ]
• Official Symbol: DAO
• Synonyms: DAO; D-amino-acid oxidase; DAMOX; D-amino acid oxidase; DAAO; OXDA; MGC35381
• Gene ID: 1610
• mRNA Refseq: NM_001917
• Protein Refseq: NP_001908
• MIM: 124050
• UniProt ID: P14920