Recombinant Human DDX21 Protein, GST-tagged

• Cat.No.: DDX21-2474H
• Product Overview: Human DDX21 full-length ORF ( NP_004719.2, 1 a.a. - 783 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 113.7 kDa
• AA Sequence: MPGKLRSDAGLESDTAMKKGETLRK QTEEKEKKEKPKSDKTEEIAEEEET VFPKAKQVKKKAEPSEVDMNSPKSK KAKKKEEPSQNDISPKTKSLRKKKE PIEKKVVSSKTKKVTKNEEPSEEEI DAPKPKKMKKEKEMNGETREKSPKL KNGFPHPEPDCNPSEAASEESNSEI EQEIPVEQKEGAFSNFPISEETIKL LKGRGVTFLFPIQAKTFHHVYSGKD LIAQARTGTGKTFSFAIPLIEKLHG ELQDRKRGRAPQVLVLAPTRELANQ VSKDFSDITKKLSVACFYGGTPYGG QFERMRNGIDILVGTPGRIKDHIQN GKLDLTKLKHVVLDEVDQMLDMGFA DQVEEILSVAYKKDSEDNPQTLLFS ATCPHWVFNVAKKYMKSTYEQVDLI GKKTQKTAITVEHLAIKCHWTQRAA VIGDVIRVYSGHQGRTIIFCETKKE AQELSQNSAIKQDAQSLHGDIPQKQ REITLKGFRNGSFGVLVATNVAARG LDIPEVDLVIQSSPPKDVESYIHRS GRTGRAGRTGVCICFYQHKEEYQLV QVEQKAGIKFKRIGVPSATEIIKAS SKDAIRLLDSVPPTAISHFKQSAEK LIEEKGAVEALAAALAHISGATSVD QRSLINSNVGFVTMILQCSIEMPNI SYAWKELKEQLGEEIDSKVKGMVFL KGKLGVCFDVPTASVTEIQEKWHDS RRWQLSVATEQPELEGPREGYGGFR GQREGSRGFRGQRDGNRRFRGQREG SRGPRGQRSGGGNKSNRSQNKGQKR SFSKAFGQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 [ Homo sapiens ]
• Official Symbol: DDX21
• Synonyms: DDX21; DEAD (Asp-Glu-Ala-Asp) box helicase 21; DEAD (Asp Glu Ala Asp) box polypeptide 21 , DEAD/H (Asp Glu Ala Asp/His) box polypeptide 21; nucleolar RNA helicase 2; GURDB; RH II/GU; RH II/Gu; gu-alpha; Gu protein; DEAD box protein 21; RNA helicase II/Gu alpha; nucleolar RNA helicase Gu; nucleolar RNA helicase II; DEAD (Asp-Glu-Ala-Asp) box polypeptide 21; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 21; GUA; RH-II/GU; RH-II/GuA; DKFZp686F21172
• Gene ID: 9188
• mRNA Refseq: NM_001256910
• Protein Refseq: NP_001243839
• MIM: 606357
• UniProt ID: Q9NR30