"DHCR24" Related Products


Recombinant Human DHCR24 protein, GST-tagged

Cat.No.: DHCR24-106H
Product Overview: Recombinant Human DHCR24(1 a.a. - 516 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.
Description: This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Source: Wheat Germ
Species: Human
Tag : GST
Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass: 86.5 kDa
Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes: Best use within three months from the date of receipt of this protein.
Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name: DHCR24 24-dehydrocholesterol reductase [ Homo sapiens ]
Official Symbol: DHCR24
Synonyms: DHCR24; 24-dehydrocholesterol reductase; delta(24)-sterol reductase; KIAA0018; seladin 1; diminuto/dwarf1 homolog; selective AD indicator 1; desmosterol-to-cholesterol enzyme; 3 beta-hydroxysterol delta 24-reductase; 3-beta-hydroxysterol delta-24-reductase; DCE; SELADIN1; Nbla03646; seladin-1;
Gene ID: 1718
mRNA Refseq: NM_014762
Protein Refseq: NP_055577
MIM: 606418
UniProt ID: Q15392

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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