Recombinant Human DPP4 protein, His-tagged
Cat.No. : | DPP4-7872H |
Product Overview : | Recombinant Human DPP4 aa. (Ser484~Val728) fused with N-terminal His tag was produced in E. coli cells. |
- Specification
- Gene Information
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Description : | The protein encoded by this gene is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | 29kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Ser484~Val728 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >98% |
Characteristic : | The isoelectric point is 6.4. |
Applications : | SDS-PAGE; WB; ELISA; IP; CoIP; Purification; Amine Reactive Labeling. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Concentration : | 200μg/mL |
Storage buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | DPP4 dipeptidyl peptidase 4 [ Homo sapiens (human) ] |
Official Symbol : | DPP4 |
Synonyms : | CD26; ADABP; ADCP2; DPPIV; TP103; ADCP-2; DPP IV; T-cell activation antigen CD26; adenosine deaminase complexing protein 2; dipeptidyl peptidase IV; dipeptidylpeptidase 4; dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); dipeptidyl peptidase 4 |
Gene ID : | 1803 |
mRNA Refseq : | NM_001935.3 |
Protein Refseq : | NP_001926.2 |
UniProt ID : | P27487 |
Products Types
◆ Recombinant Protein | ||
DPP4-116H | Recombinant Human DPP4 Protein, His-tagged | +Inquiry |
DPP4-10H | Active Recombinant Human DPP4 Protein (29-766aa), C-hIgG-tagged | +Inquiry |
DPP4-269H | Active Recombinant Human DPP4 protein(Asn29-Pro766), hFc-tagged | +Inquiry |
DPP4-792H | Recombinant Human DPP4 Protein, His-tagged | +Inquiry |
DPP4-2845H | Recombinant Human DPP4 Protein, GST-tagged | +Inquiry |
◆ Native Protein | ||
DPP4-197H | Native Human Dipeptidyl Peptidase IV | +Inquiry |
DPP4-31H | Active Native Human DPP4 | +Inquiry |
◆ Lysates | ||
DPP4-733CCL | Recombinant Cynomolgus DPP4 cell lysate | +Inquiry |
DPP4-2979HCL | Recombinant Human DPP4 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0312 | Dipeptidyl peptidase IV Inhibitor Screening Assay Kit | +Inquiry |
Kit-0314 | DPP4 Activity Fluorometric Assay Kit | +Inquiry |
Kit-0317 | DPPIV/CD26 Assay Kit | +Inquiry |
Kit-0313 | DPP IV Immunocapture Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionDPP4 plays a crucial role in glucose homeostasis by cleaving incretin hormones. In diabetes, inhibiting DPP4 can enhance the action of these hormones, promoting insulin release and lowering blood sugar levels.
Common side effects of DPP4 inhibitors include respiratory and urinary tract infections, headache, and nasopharyngitis. However, they are generally well-tolerated.
Inhibitors of DPP4 are used in the treatment of type 2 diabetes to improve glycemic control. They work by prolonging the activity of incretin hormones, such as GLP-1, which stimulate insulin secretion.
DPP4 inhibitors are often used as monotherapy or in combination with other antidiabetic medications to achieve optimal glycemic control.
DPP4 inhibitors work by enhancing the effects of incretin hormones, while other diabetes medications may act on insulin sensitivity, insulin release, or glucose absorption.
Customer Reviews (3)
Write a reviewIts purity and efficacy make it an ideal choice for precise and accurate analysis, allowing me to generate reliable results.
By incorporating the DPP4 Protein into their studies, scientists can confidently conduct their research, ushering in groundbreaking discoveries and novel insights within their respective domains.
Its exceptional purity and functionality make it an ideal choice for accurate and precise analysis, ensuring reliable and reproducible results.
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