DPP4 Protein

DPP4

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DPP4

Official Full Name dipeptidyl-peptidase 4
Background The protein encoded by this gene is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. [provided by RefSeq, Jul 2008]
Synonyms DPP4; dipeptidyl-peptidase 4; CD26; ADABP; ADCP2; DPPIV; TP103; dipeptidyl peptidase 4; ADCP-2; DPP IV; dipeptidylpeptidase 4; dipeptidyl peptidase IV; T-cell activation antigen CD26; adenosine deaminase complexing protein 2; dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2);
    • Species :
    • Bos taurus (Bovine)
    • Chicken
    • Cynomolgus Monkey
    • Homo sapiens (Human)
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Sus scrofa (Pig)
    • Zebrafish
    • Source :
    • CHO
    • E.coli
    • E.coli expression system
    • HEK293
    • HEK293T
    • Hi-5 Inscet Cell
    • Hi-5 Insect Cell
    • Human
    • Human Cell
    • Human Placenta
    • In Vitro Cell Free System
    • Insect cell
    • Mammalian Cell
    • Mammalian cells
    • S.frugiperda
    • Wheat Germ
    • Tag :
    • Fc
    • Flag
    • GST
    • His
    • His-SUMO
    • human
    • IgG1
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DPP4-1081H Active Recombinant Human DPP4, His-tagged Human HIS
    Human DPP4-215H Active Recombinant Human DPP4 protein, His-tagged E.coli His
    Human DPP4-8313H Active Recombinant Human DPP4, His tagged Hi-5 Insect Cell His
    Mouse Dpp4-413M Active Recombinant Mouse Dipeptidylpeptidase 4, His-tagged Mammalian cells His
    Cynomolgus Monkey DPP4-119C Active Recombinant Cynomolgus DPP4, Fc-tagged Human Cell Fc
    Human DPP4-31H Active Native Human DPP4 Human Placenta N/A
    Human DPP4-270H Recombinant Human DPP4 protein HEK293
    Human DPP4-116H Recombinant Human DPP4 Protein, His-tagged Insect cell His
    Human DPP4-134H Recombinant Human DPP4 Mammalian Cell His
    Human DPP4-269H Recombinant Human DPP4 protein, Fc-tagged HEK293 human/IgG1/Fc
    Human DPP4-27111TH Recombinant Human DPP4, His-tagged Hi-5 Inscet Cell His
    Human DPP4-27255TH Recombinant Human DPP4, His-tagged His
    Human DPP4-2844H Recombinant Human DPP4 Protein Wheat Germ N/A
    Human DPP4-2845H Recombinant Human DPP4 Protein, GST-tagged Wheat Germ GST
    Human DPP4-3739H Human 1PFQ N/A
    Human DPP4-4760H Recombinant Human DPP4 protein, His-tagged HEK293 His
    Human DPP4-752H Recombinant Human Dipeptidyl-peptidase 4, His-tagged S.frugiperda N/A
    Human DPP4-7872H Recombinant Human DPP4 protein, His-tagged E.coli His
    Mouse Dpp4-120M Recombinant Mouse Dpp4, Fc-tagged Human Cell Fc
    Mouse Dpp4-415M Recombinant Mouse Dpp4 protein, His-tagged HEK293 His
    Mouse DPP4-4794M Recombinant Mouse DPP4 Protein Mammalian Cell His
    Mouse Dpp4-7873M Recombinant Mouse Dpp4 protein, His-tagged E.coli His
    Mouse Dpp4-7874M Recombinant Mouse Dpp4 protein, His-tagged E.coli His
    Rat DPP4-1943R Recombinant Rat DPP4 Protein Mammalian Cell His
    Rat Dpp4-7875R Recombinant Rat Dpp4 protein, His-tagged E.coli His
    Cynomolgus Monkey DPP4-1203C Recombinant Cynomolgus DPP4 Protein, His-tagged HEK293 His
    Cynomolgus Monkey DPP4-201C Recombinant Cynomolgus DPP4 Human Cell N/A
    Cynomolgus Monkey DPP4-95C Recombinant Cynomolgus DPP4, Fc tagged Human Cell N/A
    Rhesus Macaque DPP4-1323R Recombinant Rhesus monkey DPP4 Protein, His-tagged Mammalian Cell His
    Chicken DPP4-2913C Recombinant Chicken DPP4 Mammalian Cell His
    Zebrafish DPP4-7484Z Recombinant Zebrafish DPP4 Mammalian Cell His
    Human DPP4-2979HCL Recombinant Human DPP4 cell lysate Human Cell N/A
    Cynomolgus Monkey DPP4-733CCL Recombinant Cynomolgus DPP4 cell lysate Human Cell N/A
    Human DPP4-040H Recombinant Human DPP4 Protein, His-tagged CHO His
    Mouse Dpp4-2369M Recombinant Mouse Dpp4 protein, His-SUMO-tagged E.coli His-SUMO
    Rat Dpp4-2370R Recombinant Rat Dpp4 protein, His-tagged E.coli His
    Rat Dpp4-2823R Recombinant Rat Dpp4 protein, His-SUMO-tagged E.coli His-SUMO
    Human DPP4-4118HF Recombinant Full Length Human DPP4 Protein In Vitro Cell Free System
    Human DPP4-4125HF Recombinant Full Length Human DPP4 Protein, GST-tagged In Vitro Cell Free System GST
    Human DPP4-608H Recombinant Human DPP4 Protein, His-tagged CHO His
    Human DPP4-797HFL Recombinant Full Length Human DPP4 Protein, C-Flag-tagged Mammalian cells Flag
    Bos taurus (Bovine) RFL19301BF Recombinant Full Length Bovine Dipeptidyl Peptidase 4(Dpp4) Protein, His-Tagged E.coli expression system His
    Homo sapiens (Human) RFL31481HF Recombinant Full Length Human Dipeptidyl Peptidase 4(Dpp4) Protein, His-Tagged E.coli expression system His
    Sus scrofa (Pig) RFL8847SF Recombinant Full Length Pig Dipeptidyl Peptidase 4(Dpp4) Protein, His-Tagged E.coli expression system His
    Human DPP4-197H Native Human Dipeptidyl Peptidase IV Human Placenta N/A
    Human DPP4-2540H Recombinant Human DPP4 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human DPP4-5830H Recombinant Human DPP4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Dpp4-2641M Recombinant Mouse Dpp4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Kit-0312 Dipeptidyl peptidase IV Inhibitor Screening Assay Kit N/A
    Kit-0313 DPP IV Immunocapture Activity Assay Kit N/A
    Kit-0314 DPP4 Activity Fluorometric Assay Kit N/A
    Kit-0315 DPP4 Inhibitor Screening Kit N/A
    Kit-0316 DPPIV drug discovery Kit N/A
    Kit-0317 DPPIV/CD26 Assay Kit N/A

    DPP4 involved in several pathways and played different roles in them. We selected most pathways DPP4 participated on our site, such as Incretin synthesis, secretion, and inactivation, Metabolism of proteins, Peptide hormone metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with DPP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Incretin synthesis, secretion, and inactivation GRP; GPR119; SPCS3; CDX2; PCSK1; O3far1; GPR120; SLC38A8; DPP4
    Metabolism of proteins SLC34A2A; MPDU1; DPAGT1; SAE1; PCSK1; MBOAT4; DOHH; GZMH; GALNTL5; BCS1L
    Peptide hormone metabolism GZMH; SLC30A6; EXOC8; CMA1; CGB7; GPR119; CPN1; RAB27A; CDX2; CGB5
    Protein digestion and absorption COL4A1; SLC1A1; MEP1B; PRSS1; ATP1A3; COL6A5; KCNK5; SLC15A1; ATP1A2; COL24A1
    Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) PCSK1; DPP4; GPR119

    DPP4 has several biochemical functions, for example, dipeptidyl-peptidase activity, identical protein binding, protease binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DPP4 itself. We selected most functions DPP4 had, and list some proteins which have the same functions with DPP4. You can find most of the proteins on our site.

    Function Related Protein
    dipeptidyl-peptidase activity NAALAD2; DPP3; DPP8; DPEP3; DPP4; DPP7; DPEP2; DPEP1; FAP; PRCP
    identical protein binding SOD1; EDC3; COL18A1; EPHA4; HCN4; PSMA7; ST13; ORAI1; BRAP; COL2A1
    protease binding POLG; TNFRSF10A; INSL3; FURIN; SERPINC1; SERPINA1; INS2; Serpina1c; ANXA2; CRADD
    protein binding CCDC42; DERL3; DPH2; SH2D2A; DCAF11; DDX42; FRK; GLS2; a; CDCA7L
    protein homodimerization activity VWF; CRTAM; ADRB2; FGFR1OP2; ENG; SYT14; FAM109A; ACOT7; BAX; GSTM2
    receptor binding PVRL1B; FGF24; PIPOX; APLN; IDH1; ECI2; CNTFR; MAP7; DRD1A; PAOX
    serine-type endopeptidase activity KLK1; MCPT2; PRSS48; CFI; MMP2; PRSS54; DPP4; GZMB; KLK1B1; ST14
    serine-type peptidase activity PLAUA; TMPRSS2; OVCH2; KLK1B22; PREP; PLAUB; ELA3L; TMPRSS13B; SLC38A8; KLK1B9
    virus receptor activity PVRL2; ANPEP; SLAMF1; ACE2; TYRO3; SERPINB4; SLC10A1; CD46; CD4; ICAM1

    DPP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPP4.

    CXCL11; CXCL10; CXCL2; CCL11; CXCL9

    Gierer, S; Muller, MA; et al. Inhibition of Proprotein Convertases Abrogates Processing of the Middle Eastern Respiratory Syndrome Coronavirus Spike Protein in Infected Cells but Does Not Reduce Viral Infectivity. JOURNAL OF INFECTIOUS DISEASES 211:889-897(2015).
    Tiezzi, F; Parker-Gaddis, KL; et al. A Genome-Wide Association Study for Clinical Mastitis in First Parity US Holstein Cows Using Single-Step Approach and Genomic Matrix Re-Weighting Procedure. PLOS ONE 10:-(2015).

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