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Recombinant Human EEF2K Protein, GST-tagged

Cat.No. : EEF2K-3076H
Product Overview : Human EEF2K full-length ORF ( AAH32665, 1 a.a. - 725 a.a.) recombinant protein with GST-tag at N-terminal.
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Description : This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 105.49 kDa
AA Sequence : MADEDLIFRLEGVDGGQSPRAGRDG DSDGDSDDEEGYFICPITDDPSSNQ NVNSKVNKYYSNLTKSERYSSSGSP ANSFHFKEAWKHAIQKAKHMPDPWA EFHLEDIATERATRHRYNAVTGEWL DDEVLIKMASQPFGRGAMRECFRTK KLSNFLHAQQWKGASNYVAKRYIEP VDRDVYFEDVRLQMEAKLWGEEYNR HKPPKQVDIMQMCIIELKDRPGKPL FHLEHYIEGKYIKYNSNSGFVRDDN IRLTPQAFSHFTFERSGHQLIVVDI QGVGDLYTDPQIHTETGTDFGDGNL GVRGMALFFYSHACNRICESMGLAP FDLSPRERDAVNQNTKLLQSAKTIL RGTEEKCGSPRVRTLSGSRPPLLRP LSENSGDENMSDVTFDSLPSSPSSA TPHSQKLDHLHWPVFSDLDNMASRD HDHLDNHRESENSGDSGYPSEKRGE LDDPEPREHGHSYSNRKYESDEDSL GSSGRVCVEKWNLLNSSRLHLPRAS AVALEVQRLNALDLEKKIGKSILGK VHLAMVRYHEGGRFCEKGEEWDQES AVFHLEHAANLGELEAIVGLGLMYS QLPHHILADVSLKETEENKTKGFDY LLKAAEAGDRQSMILVARAFDSGQN LSPDRCQDWLEALHWYNTALEMTDC DEGGEYDGMQDEPRYMMLAREAEML FTGGYGLEKDPQRSGDLYTQAAEAA MEAMKGRLANQYYQKAEEAWAQMEE
Applications : Kinase Assay
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : EEF2K eukaryotic elongation factor-2 kinase [ Homo sapiens ]
Official Symbol : EEF2K
Synonyms : EEF2K; eukaryotic elongation factor-2 kinase; eukaryotic elongation factor 2 kinase; eEF 2K; eEF-2 kinase; elongation factor-2 kinase; eukaroytic elongation factor 2 kinase; calmodulin-dependent protein kinase III; calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase; calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase; eEF-2K; HSU93850; MGC45041;
Gene ID : 29904
mRNA Refseq : NM_013302
Protein Refseq : NP_037434
MIM : 606968
UniProt ID : O00418

Not For Human Consumption!

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