Active Recombinant Human EIF2AK3 Protein, GST-tagged
Cat.No. : | EIF2AK3-3150H |
Product Overview : | Human EIF2AK3 (NP_004827.3, 536 a.a. - 1116 a.a.) partial recombinant protein with GST tag expressed in Escherichia coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015] |
Source : | E. coli |
Species : | Human |
Tag : | GST |
Form : | Liquid |
Bio-activity : | The activity was determined by IMAPTM assay. The enzyme was incubated with fluorescein labeled peptide and phosphorylation was detected by IMAPTM technology (fluorescence polarization). Substrate: SRPKtide. ATP: 100 μM. |
Molecular Mass : | 94 kDa |
Purity : | 51 % by SDS-PAGE/CBB staining |
Applications : | Functional Study SDS-PAGE |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.05% Brij35, 1 mM DTT, 10% glycerol) |
Gene Name : | EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 [ Homo sapiens ] |
Official Symbol : | EIF2AK3 |
Synonyms : | EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3; PEK; PERK; hsPEK; pancreatic EIF2-alpha kinase; PRKR-like endoplasmic reticulum kinase; eukaryotic translation initiation factor 2 alpha kinase 3; WRS; DKFZp781H1925; |
Gene ID : | 9451 |
mRNA Refseq : | NM_004836 |
Protein Refseq : | NP_004827 |
MIM : | 604032 |
UniProt ID : | Q9NZJ5 |
Products Types
◆ Recombinant Protein | ||
EIF2AK3-337H | Recombinant Human EIF2AK3 Protein, MYC/DDK-tagged | +Inquiry |
Eif2ak3-2772M | Recombinant Mouse Eif2ak3 Protein, Myc/DDK-tagged | +Inquiry |
EIF2AK3-1020H | Recombinant Human EIF2AK3 Protein, His-tagged | +Inquiry |
EIF2AK3-1413H | Recombinant Human EIF2AK3 Protein, His-tagged | +Inquiry |
EIF2AK3-819H | Recombinant Human EIF2AK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
EIF2AK3-6673HCL | Recombinant Human EIF2AK3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket