Recombinant Human ENPP1 Protein

• Cat.No.: ENPP1-3320H
• Product Overview: Human ENPP1 full-length ORF (NP_006199.1) recombinant protein without tag.

Specification

• Description: This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Form: Liquid
• Molecular Mass: 99.9 kDa
• AA Sequence: MDVGEEPLEKAARARTAKDPNTYKV LSLVLSVCVLTTILGCIFGLKPSCA KEVKSCKGRCFERTFGNCRCDAACV ELGNCCLDYQETCIEPEHIWTCNKF RCGEKRLTRSLCACSDDCKDKGDCC INYSSVCQGEKSWVEEPCESINEPQ CPAGFETPPTLLFSLDGFRAEYLHT WGGLLPVISKLKKCGTYTKNMRPVY PTKTFPNHYSIVTGLYPESHGIIDN KMYDPKMNASFSLKSKEKFNPEWYK GEPIWVTAKYQGLKSGTFFWPGSDV EINGIFPDIYKMYNGSVPFEERILA VLQWLQLPKDERPHFYTLYLEEPDS SGHSYGPVSSEVIKALQRVDGMVGM LMDGLKELNLHRCLNLILISDHGME QGSCKKYIYLNKYLGDVKNIKVIYG PAARLRPSDVPDKYYSFNYEGIARN LSCREPNQHFKPYLKHFLPKRLHFA KSDRIEPLTFYLDPQWQLALNPSER KYCGSGFHGSDNVFSNMQALFVGYG PGFKHGIEADTFENIEVYNLMCDLL NLTPAPNNGTHGSLNHLLKNPVYTP KHPKEVHPLVQCPFTRNPRDNLGCS CNPSILPIEDFQTQFNLTVAEEKII KHETLPYGRPRVLQKENTICLLSQH QFMSGYSQDILMPLWTSYTVDRNDS FSTEDFSNCLYQDFRIPLSPVHKCS FYKNNTKVSYGFLSPPQLNKNSSGI YSEALLTTNIVPMYQSFQVIWRYFH DTLLRKYAEERNGVNVVSGPVFDFD YDGRCDSLENLRQKRRVIRNQEILI PTHFFIVLTSCKDTSQTPLHCENLD TLAFILPHRTDNSESCVHGKHDSSW VEELLMLHRARITDVEHITGLSFYQ QRKEPVSDILKLKTHLPTFSQED
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Usage: Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH 8.0 containing 2% glycerol.

Gene Information

• Gene Name: ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 [ Homo sapiens ]
• Official Symbol: ENPP1
• Synonyms: ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase 1; M6S1, NPPS, PDNP1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1; PC 1; PCA1; E-NPP 1; Ly-41 antigen; alkaline phosphodiesterase 1; plasma-cell membrane glycoprotein 1; plasma-cell membrane glycoprotein PC-1; membrane component chromosome 6 surface marker 1; phosphodiesterase I/nucleotide pyrophosphatase 1; membrane component, chromosome 6, surface marker 1; M6S1; NPP1; NPPS; PC-1; ARHR2; PDNP1
• Gene ID: 5167
• mRNA Refseq: NM_006208
• Protein Refseq: NP_006199
• MIM: 173335
• UniProt ID: P22413