Recombinant Human ENPP2 protein, His-tagged
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
|Product Overview :||Recombinant Human ENPP2 protein (Asp49-Ile863) was fused to His-tag at the N-terminus and expressed in human 293 cells (HEK293).|
|Description :||Autotaxin also known as ectonucleotide pyrophosphatase / phosphodiesterase family member 2 (E-NPP 2 or ENPP2), Extracellular lysophospholipase D (LysoPLD), Autotaxin (ATX or ATX-X), which belongs to the nucleotide pyrophosphatase / phosphodiesterase family. ENPP2 contains two SMB (somatomedin-B) domains. ENPP2 hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. ENPP2 can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. ENPP2 stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein.|
|Predicted N Terminal :||His|
|Form :||Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH 7.5, 10% trehalose.|
|Molecular Mass :||The protein has a calculated MW of 94.5 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE).|
|Protein length :||Asp49-Ile863|
|Endotoxin :||Less than 1.0 EU per μg by the LAL method.|
|Purity :||>95% as determined by SDS-PAGE.|
|Storage :||For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
|Reconstitution :||It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4°C before opening to recover the entire contents.|
|SDS-PAGE of ENPP2-63H :||
Human ENPP-2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
|Gene Name :||ENPP2|
|Official Symbol :||ENPP2|
|Synonyms :||ENPP-2,E-NPP 2,Autotaxin,LysoPLD,ATX,PDNP2,ATX-X,NPP2,PD-IALPHA|
|Gene ID :||5168|
|mRNA Refseq :||NM_006209.5|
|Protein Refseq :||NP_006200.3|
|UniProt ID :||Q13822|
◆ Recombinant Protein
|ENPP2-013H||Recombinant Human ENPP2 Protein, His-tagged||+Inquiry|
|ENPP2-567H||Recombinant Human ENPP2 Protein, His-tagged||+Inquiry|
|Enpp2-1190M||Recombinant Mouse Enpp2 Protein, His-tagged||+Inquiry|
|Enpp2-553R||Recombinant Rat Enpp2 Protein, His-tagged||+Inquiry|
|ENPP2-552H||Recombinant Human ENPP2 Protein, His-tagged||+Inquiry|
|ENPP2-1939MCL||Recombinant Mouse ENPP2 cell lysate||+Inquiry|
|ENPP2-1556HCL||Recombinant Human ENPP2 cell lysate||+Inquiry|