Recombinant Human EPCAM Protein, Strep-tagged
Cat.No. : | EPCAM-349H |
Product Overview : | Recombinant Human EPCAM Protein, Strep-tagged is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Lys 265 (Accession # AAH14785.1). Predicted N-terminus: Gln 24. This protein carries a twin strep tag at the C-terminus. The protein has a calculated MW of 30.4 kDa. The protein migrates as 33-48 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
- Specification
- Gene Information
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Source : | HEK293 |
Species : | Human |
Tag : | Strep |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. |
Molecular Mass : | 30.4 kDa |
Protein length : | Gln 24 - Lys 265 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Notes : | Please avoid repeated freeze-thaw cycles. |
Stability : | No activity loss is observed after storage at: 4-8 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4 centigrade before opening to recover the entire contents. |
Gene Name : | EPCAM epithelial cell adhesion molecule [ Homo sapiens ] |
Official Symbol : | EPCAM |
Synonyms : | EPCAM; 17 1A; 323/A3; CD326; CO 17A; EGP 2; EGP34; EGP40; Ep CAM; ESA; GA733 2; HEA125; KS1/4; KSA; Ly74; MH99; MK 1; MOC31; TACST 1; TROP1; M4S1; MK-1; DIAR5; EGP-2; MIC18; EGP314; HNPCC8; TACSTD1; GA733-2; |
Gene ID : | 4072 |
mRNA Refseq : | NM_002354 |
Protein Refseq : | NP_002345 |
MIM : | 185535 |
UniProt ID : | P16422 |
Products Types
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EPCAM-215H | Active Recombinant Human EPCAM Protein (Gln24-Lys265), C-His tagged, Animal-free, Carrier-free | +Inquiry |
EPCAM-1430H | Recombinant Human EPCAM Protein, His&GST-tagged | +Inquiry |
◆ Lysates | ||
EPCAM-001CCL | Recombinant Cynomolgus EPCAM cell lysate | +Inquiry |
EPCAM-2525HCL | Recombinant Human EPCAM cell lysate | +Inquiry |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionEpCAM is highly expressed in epithelial tissues and some cancer cells.
It has a controversial role in cell adhesion, possibly contributing to both cell-cell adhesion and anti-adhesive properties.
EpCAM primarily functions in cell signaling, proliferation, and migration.
It often has a pro-tumorigenic role, promoting cancer cell proliferation, migration, and invasion.
EpCAM is used as a biomarker to detect and isolate circulating tumor cells.
Strategies include developing EpCAM-targeted therapies for cancer treatment.
Genetic alterations in EpCAM are linked to some hereditary cancer syndromes.
Customer Reviews (3)
Write a reviewReliable for assays, satisfied customer.
High-quality product, consistent results.
Quick delivery, product as described.
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