Recombinant Human F10 Protein, GST-tagged

PRODUCTS

Home / Products / Recombinant Human F10 Protein, GST-tagged

Recombinant Human F10 Protein, GST-tagged

F10 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : F10-3601H
Product Overview : Human F10 full-length ORF ( AAH46125, 32 a.a. - 488 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq, Aug 2015]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 76.01 kDa
AA Sequence : NNILARVTRANSFLE EMKKGHLERECMEET CSYEEAREVFEDSDK TNEFWNKYKDGDQCE TSPCQNQGKCKDGLG EYTCTCLEGFEGKNC ELFTRKLCSLDNGDC DQFCHEEQNSVVCSC ARGYTLADNGKACIP TGPYPCGKQTLERRK RSVAQATSSSGEAPD SITWKPYDAADLDPT ENPFDLLDFNQTQPE RGDNNLTRIVGGQEC KDGECPWQALLINEE NEGFCGGTILSEFYI LTAAHCLYQAKRFKV RVGDRNTEQEEGGEA VHEVEVVIKHNRFTK ETYDFDIAVLRLKTP ITFRMNVAPACLPER DWAESTLMTQKTGIV SGFGRTHEKGRQSTR LKMLEVPYVDRNSCK LSSSFIITQNMFCAG YDTKQEDACQGDSGG PHVTRFKDTYFVTGI VSWGEGCARKGKYGI YTKVTAFLKWIDRSM KTRGLPKAKSHAPEV ITSSPLK
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : F10 coagulation factor X [ Homo sapiens ]
Official Symbol : F10
Synonyms : F10; coagulation factor X; factor Xa; prothrombinase; Stuart-Prower factor; FX; FXA;
Gene ID : 2159
mRNA Refseq : NM_000504
Protein Refseq : NP_000495
MIM : 613872
UniProt ID : P00742

Online Inquiry


  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved.