Recombinant Human FEN1 Protein (G2-K380), Tag Free
Cat.No. : | FEN1-1235H |
Product Overview : | Recombinant Human GG-FEN1(G2-K380 end) Protein was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA. |
Source : | E. coli |
Species : | Human |
Tag : | No tag |
Form : | Liquid |
Protein Length : | G2-K380 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | FEN1 flap structure-specific endonuclease 1 [ Homo sapiens (human) ] |
Official Symbol : | FEN1 |
Synonyms : | FEN1; flap structure-specific endonuclease 1; RAD2; flap endonuclease 1; DNase IV; FEN 1; maturation factor 1; MF1; maturation factor-1; FEN-1; |
Gene ID : | 2237 |
mRNA Refseq : | NM_004111 |
Protein Refseq : | NP_004102 |
MIM : | 600393 |
UniProt ID : | P39748 |
Products Types
◆ Recombinant Protein | ||
FEN1-1477H | Recombinant Human FEN1 Protein, His-tagged | +Inquiry |
Fen1-2986M | Recombinant Mouse Fen1 Protein, Myc/DDK-tagged | +Inquiry |
FEN1-1236H | Recombinant Human FEN1 Protein (G2-K380), His/Strep tagged | +Inquiry |
FEN1-360H | Recombinant Human FEN1 protein(Met1~Thr195), His-tagged | +Inquiry |
FEN1-1509R | Recombinant Rhesus Macaque FEN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FEN1-6264HCL | Recombinant Human FEN1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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