Recombinant Human FEN1 protein, MYC/DDK-tagged

• Cat.No.: FEN1-4018H
• Product Overview: Recombinant Human FEN1 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 42.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: FEN1 flap structure-specific endonuclease 1 [ Homo sapiens ]
• Official Symbol: FEN1
• Synonyms: FEN1; flap structure-specific endonuclease 1; RAD2; flap endonuclease 1; DNase IV; FEN 1; maturation factor 1; MF1; maturation factor-1; FEN-1
• Gene ID: 2237
• mRNA Refseq: NM_004111
• Protein Refseq: NP_004102
• MIM: 600393
• UniProt ID: P39748
• Chromosome Location: 11q12
• Pathway: Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; DNA Repair, organism-specific biosystem
• Function: 5-3 exonuclease activity; 5-flap endonuclease activity; 5-flap endonuclease activity; DNA binding; damaged DNA binding; double-stranded DNA binding; double-stranded DNA specific exodeoxyribonuclease activity; endonuclease activity; exonuclease activity; magnesium ion binding; manganese ion binding; protein binding; ribonuclease H activity