Recombinant Human FGF2 Protein, MYC/DDK-tagged, C13 and N15-labeled
Cat.No. : | FGF2-155H |
Product Overview : | FGF2 MS Standard C13 and N15-labeled recombinant protein (NP_001997) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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- Gene Information
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Description : | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 30.6 kDa |
AA Sequence : | MVGVGGGDVEDVTPRPGGCQISGRG ARGCNGIPGAAAWEAALPRRRPRRH PSVNPRSRAAGSPRTRGRRTEERPS GSRLGDRGRGRALPGGRLGGRGRGR APERVGGRGRGRGTAAPRAAPAARG SRPGPAGTMAAGSITTLPALPEDGG SGAFPPGHFKDPKRLYCKNGGFFLR IHPDGRVDGVREKSDPHIKLQLQAE ERGVVSIKGVCANRYLAMKEDGRLL ASKCVTDECFFFERLESNNYNTYRS RKYTSWYVALKRTGQYKLGSKTGPG QKAILFLPMSAKSTRTRPLEQKLIS EEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | FGF2 fibroblast growth factor 2 [ Homo sapiens (human) ] |
Official Symbol : | FGF2 |
Synonyms : | FGF2; fibroblast growth factor 2; BFGF; FGF-2; FGFB; HBGF-2; fibroblast growth factor 2; basic fibroblast growth factor bFGF; fibroblast growth factor 2 (basic); heparin-binding growth factor 2; prostatropin |
Gene ID : | 2247 |
mRNA Refseq : | NM_002006 |
Protein Refseq : | NP_001997 |
MIM : | 134920 |
UniProt ID : | P09038 |
Products Types
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◆ Native Protein | ||
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FGF2-34B | Active Native Bovine bFGF | +Inquiry |
◆ Lysates | ||
FGF2-638HCL | Recombinant Human FGF2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionFGF2 promotes cell migration and angiogenesis and regulates bone homeostatic balance.
FGF2 is widely expressed in the nervous system.
FGF2 is mainly expressed in tissues such as mammary glands and ovaries of sheep.
FGF1 has a high degree of homology with FGF2.
FGF2 is involved in diseases such as cardiovascular disease, breast disease and bone homeostasis.
FGF2 negatively regulates bone homeostasis.
Customer Reviews (2)
Write a reviewThe technical expert communicated with me in time to understand the progress of my experiment and gave me suggestions for improvement.
The purchased protein is suitable for WB experiments and I am satisfied with the results.
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