Recombinant Human FSCN1 Protein, GST-tagged

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Recombinant Human FSCN1 Protein, GST-tagged

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Cat.No. : FSCN1-4511H
Product Overview : Human FSCN1 full-length ORF (NP_003079.1, 1 a.a. - 493 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 80.63 kDa
AA Sequence : MTANGTAEAV QIQFGLINCG NKYLTAEAFG FKVNASASSL KKKQIWTLEQ PPDEAGSAAV CLRSHLGRYL AADKDGNVTC EREVPGPDCR FLIVAHDDGR WSLQSEAHRR YFGGTEDRLS CFAQTVSPAE KWSVHIAMHP QVNIYSVTRK RYAHLSARPA DEIAVDRDVP WGVDSLITLA FQDQRYSVQT ADHRFLRHDG RLVARPEPAT GYTLEFRSGK VAFRDCEGRY LAPSGPSGTL KAGKATKVGK DELFALEQSC AQVVLQAANE RNVSTRQGMD LSANQDEETD QETFQLEIDR DTKKCAFRTH TGKYWTLTAT GGVQSTASSK NASCYFDIEW RDRRITLRAS NGKFVTSKKN GQLAASVETA GDSELFLMKL INRPIIVFRG EHGFIGCRKV TGTLDANRSS YDVFQLEFND GAYNIKDSTG KYWTVGSDSA VTSSGDTPVD FFFEFCDYNK VAIKVGGRYL KGDHAGVLKA SAETVDPASL WEY
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : FSCN1 fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) [ Homo sapiens ]
Official Symbol : FSCN1
Synonyms : FSCN1; fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus); singed (Drosophila) like (sea urchin fascin homolog like), SNL; fascin; actin bundling protein; FLJ38511; p55; Singed; drosophila; homolog like; 55 kDa actin-bundling protein; singed-like (fascin homolog, sea urchin); HSN; SNL; FAN1; FLJ43305;
Gene ID : 6624
mRNA Refseq : NM_003088
Protein Refseq : NP_003079
MIM : 602689
UniProt ID : Q16658

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