Recombinant Human FSCN1 Protein, GST-tagged

• Cat.No.: FSCN1-4511H
• Product Overview: Human FSCN1 full-length ORF (NP_003079.1, 1 a.a. - 493 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 80.63 kDa
• AA Sequence: MTANGTAEAVQIQFGLINCGNKYLT AEAFGFKVNASASSLKKKQIWTLEQ PPDEAGSAAVCLRSHLGRYLAADKD GNVTCEREVPGPDCRFLIVAHDDGR WSLQSEAHRRYFGGTEDRLSCFAQT VSPAEKWSVHIAMHPQVNIYSVTRK RYAHLSARPADEIAVDRDVPWGVDS LITLAFQDQRYSVQTADHRFLRHDG RLVARPEPATGYTLEFRSGKVAFRD CEGRYLAPSGPSGTLKAGKATKVGK DELFALEQSCAQVVLQAANERNVST RQGMDLSANQDEETDQETFQLEIDR DTKKCAFRTHTGKYWTLTATGGVQS TASSKNASCYFDIEWRDRRITLRAS NGKFVTSKKNGQLAASVETAGDSEL FLMKLINRPIIVFRGEHGFIGCRKV TGTLDANRSSYDVFQLEFNDGAYNI KDSTGKYWTVGSDSAVTSSGDTPVD FFFEFCDYNKVAIKVGGRYLKGDHA GVLKASAETVDPASLWEY
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FSCN1 fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) [ Homo sapiens ]
• Official Symbol: FSCN1
• Synonyms: FSCN1; fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus); singed (Drosophila) like (sea urchin fascin homolog like), SNL; fascin; actin bundling protein; FLJ38511; p55; Singed; drosophila; homolog like; 55 kDa actin-bundling protein; singed-like (fascin homolog, sea urchin); HSN; SNL; FAN1; FLJ43305
• Gene ID: 6624
• mRNA Refseq: NM_003088
• Protein Refseq: NP_003079
• MIM: 602689
• UniProt ID: Q16658