| Cat.No.: | FXR1-941H |
| Product Overview: | Recombinant Human FXR1(1 a.a. - 621 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ. |
| Description: | The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. Theseproteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene. |
| Source: | Wheat Germ |
| Species: | Human |
| Tag: | GST |
| Form: | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Molecular Mass: | 96.1 kDa |
| AA Sequence: | MAELTVEVRGSNGAFYKGFIKDVHEDPLTVVFENNWQPERQVPFNEVRLPPPPDIKKEISEGDEVEVYSRANDQE PCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANENAHKDF KKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVV REDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKN GKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQL RQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVS GGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESD TASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGE EKINTLKEENTQEAAVLNGVS |
| Applications: | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
| Notes: | Best use within three months from the date of receipt of this protein. |
| Storage: | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Gene Name: | FXR1 fragile X mental retardation, autosomal homolog 1 [ Homo sapiens ] |
| Official Symbol: | FXR1 |
| Synonyms: | FXR1; fragile X mental retardation, autosomal homolog 1; fragile X mental retardation syndrome-related protein 1; hFXR1p; FXR1P; |
| Gene ID: | 8087 |
| mRNA Refseq: | NM_001013438 |
| Protein Refseq: | NP_001013456 |
| MIM: | 600819 |
| UniProt ID: | P51114 |
| Chromosome Location: | 3q28 |
| Pathway: | RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; |
| Function: | G-quadruplex RNA binding; RNA binding; mRNA 3-UTR binding; |
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