Recombinant Human GHRH Protein, GST-tagged

• Cat.No.: GHRH-4888H
• Product Overview: Human GHRH full-length ORF ( NP_066567.1, 1 a.a. - 108 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 38.8 kDa
• AA Sequence: MPLWVFFFVILTLSNSSHCSPPPPL TLRMRRYADAIFTNSYRKVLGQLSA RKLLQDIMSRQQGESNQERGARARL GRQVDSMWAEQKQMELESILVALLQ KHSRNSQG
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GHRH growth hormone releasing hormone [ Homo sapiens ]
• Official Symbol: GHRH
• Synonyms: GHRH; growth hormone releasing hormone; GHRF; somatoliberin; sermorelin; somatocrinin; somatorelin; growth hormone-releasing factor; growth hormone-releasing hormone; GRF; INN; MGC119781
• Gene ID: 2691
• mRNA Refseq: NM_001184731
• Protein Refseq: NP_001171660
• MIM: 139190
• UniProt ID: P01286

Reviews

08/24/2017

GHRH is extensively used in protein electron microscopy structure analysis due to its compatibility with this technique, providing crucial insights into molecular architectures.

03/05/2017

One aspect that sets the GHRH Protein apart is the excellent technical support provided by the manufacturer.

09/13/2016

I have found the GHRH Protein to be highly stable, enabling long-term experiments without compromising its performance.

Q&As

Is GHRH therapy only used for growth-related issues?

No, it's also being explored for its potential in other conditions like muscle wasting diseases and cognitive disorders.

How long does it usually take to see the effects of GHRH therapy?

Effects on growth may take several months to become noticeable, depending on the individual and the underlying condition.

How does GHRH affect the body?

It stimulates the pituitary gland to release growth hormone, which regulates growth, metabolism, and body composition.

What conditions can benefit from GHRH therapy?

GHRH therapy is beneficial for children with growth hormone deficiencies and adults with certain growth hormone-related disorders.

Are there any age restrictions for GHRH therapy?

Typically, it's used in children and adults with specific hormone deficiencies or growth-related conditions.