Recombinant Human GPR56 Protein, GST-tagged

• Cat.No.: GPR56-5254H
• Product Overview: Human GPR56 full-length ORF ( AAH08770.1, 1 a.a. - 693 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 104.1 kDa
• AA Sequence: MTPQSLLQTTLFLLSLLFLVQGAHG RGHREDFRFCSQRNQTHRSSLHYKP TPDLRISIENSEEALTVHAPFPAAH PASRSFPDPRGLYHFCLYWNRHAGR LHLLYGKRDFLLSDKASSLLCFQHQ EESLAQGPPLLATSVTSWWSPQNIS LPSAASFTFSFHSPPHTAAHNASVD MCELKRDLQLLSQFLKHPQKASRRP SAAPASQQLQSLESKLTSVRFMGDM VSFEEDRINATVWKLQPTAGLQDLH IHSRQEEEQSEIMEYSVLLPRTLFQ RTKGRSGEAEKRLLLVDFSSQALFQ DKNSSHVLGEKVLGIVVQNTKVANL TEPVVLTFQHQLQPKNVTLQCVFWV EDPTLSSPGHWSSAGCETVRRETQT SCFCNHLTYFAVLMVSSVEVDAVHK HYLSLLSYVGCVVSALACLVTIAAY LCSRVPLPCRRKPRDYTIKVHMNLL LAVFLLDTSFLLSEPVALTGSEAGC RASAIFLHFSLLTCLSWMGLEGYNL YRLVVEVFGTYVPGYLLKLSAMGWG FPIFLVTLVALVDVDNYGPIILAVH RTPEGVIYPSMCWIRDSLVSYITNL GLFSLVFLFNMAMLATMVVQILRLR PHTQKWSHVLTLLGLSLVLGLPWAL IFFSFASGTFQLVVLYLFSIITSFQ GFLIFIWYWSMRLQARGGPSPLKSN SDSARLPISSGSTSSSRI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GPR56 G protein-coupled receptor 56 [ Homo sapiens ]
• Official Symbol: GPR56
• Synonyms: GPR56; G protein-coupled receptor 56; G-protein coupled receptor 56; TM7LN4; TM7XN1; 7-transmembrane protein with no EGF-like N-terminal domains-1; BFPP; DKFZp781L1398
• Gene ID: 9289
• mRNA Refseq: NM_001145770
• Protein Refseq: NP_001139242
• MIM: 604110
• UniProt ID: Q9Y653