Active Recombinant Human HAVCR2 Protein, Fc-Tagged
Cat.No. : | HAVCR2-01H |
Product Overview : | Mouse myeloma cell line, NS0-derived Recombinant Human HAVCR2 Protein, Fc-Tagged |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. |
Source : | Mouse myeloma cell line |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized |
Bio-activity : | Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human Galectin‑9 at 500 ng/mL can bind Recombinant Human TIM-3 Fc Chimera with an apparent Kd <30 nM. |
Molecular Mass : | 46.4 kDa (monomer) |
N-terminal Sequence Analysis : | Ser22 |
Endotoxin : | <0.01 EU per 1 μg of the protein by the LAL method. |
Purity : | >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution : | Reconstitute at 100 μg/mL in sterile PBS. |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Gene Name : | HAVCR2 hepatitis A virus cellular receptor 2 [ Homo sapiens (human) ] |
Official Symbol : | HAVCR2 |
Synonyms : | CD366; FLJ14428; HAVCR2; HAVcr-2; hepatitis A virus cellular receptor 2; kidney injury molecule-3; KIM-3; SPTCL; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain-containing protein 3; TIM 3; TIM3 T-cell membrane protein 3; TIM3; TIM-3; TIMD3; TIMD-3; TIMD3KIM-3 |
Gene ID : | 84868 |
mRNA Refseq : | NM_032782.5 |
Protein Refseq : | NP_116171.3 |
MIM : | 606652 |
UniProt ID : | Q8TDQ0 |
Products Types
◆ Recombinant Protein | ||
HAVCR2-956H | Recombinant Human HAVCR2 Protein, His-tagged | +Inquiry |
HAVCR2-739M | Recombinant Mouse HAVCR2 Protein, Fc-tagged | +Inquiry |
HAVCR2-705H | Active Recombinant Human HAVCR2 Protein, His-Avi-tagged, Biotinylated | +Inquiry |
Havcr2-138M | Recombinant Mouse Havcr2 Protein, His (Fc)-Avi-tagged | +Inquiry |
HAVCR2-2023H | Recombinant Human HAVCR2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
HAVCR2-001CCL | Recombinant Cynomolgus HAVCR2 cell lysate | +Inquiry |
HAVCR2-995MCL | Recombinant Mouse HAVCR2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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