Recombinant Human HINT1 Protein, GST-tagged

• Cat.No.: HINT1-4750H
• Product Overview: Human HINT1 full-length ORF ( AAH01287, 1 a.a. - 126 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein that hydrolyzes purine nucleotide phosphoramidates substrates, including AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif. This gene is considered a tumor suppressor gene. In addition, mutations in this gene can cause autosomal recessive neuromyotonia and axonal neuropathy. There are several related pseudogenes on chromosome 7. Several transcript variants have been observed. [provided by RefSeq, Dec 2015]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 39.6 kDa
• AA Sequence: MADEIAKAQVARPGGDTIFGKIIRK EIPAKIIFEDDRCLAFHDISPQAPT HFLVIPKKHISQISVAEDDDESLLG HLMIVGKKCAADLGLNKGYRMVVNE GSDGGQSVYHVHLHVLGGRQMHWPP G
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HINT1 histidine triad nucleotide binding protein 1 [ Homo sapiens ]
• Official Symbol: HINT1
• Synonyms: HINT1; histidine triad nucleotide binding protein 1; HINT, histidine triad nucleotide binding protein , PRKCNH1; histidine triad nucleotide-binding protein 1; PKCI 1; protein kinase C inhibitor 1; adenosine 5-monophosphoramidase; protein kinase C-interacting protein 1; HINT; PKCI-1; PRKCNH1; FLJ30414; FLJ32340
• Gene ID: 3094
• mRNA Refseq: NM_005340
• Protein Refseq: NP_005331
• MIM: 601314
• UniProt ID: P49773