Recombinant Human Histone Deacetylase 10, GST-tagged

• Cat.No.: HDAC10-1588H
• Product Overview: Recombinant human HDAC10 (1-482) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Cat. No.: HDAC10-1588H
• Description: HDAC10 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. HDAC10 belongs to class II of the histone deacetylase family that catalyzes the deacetylation of lysine residues in the N-terminal tail of histones and represses transcription in large multiprotein complexes with transcriptional co-repressors.
• Applications: HDAC Assay, Western Blot
• Molecular Weight: 77 kDa
• Expression System: Sf9 insect cells using baculovirus
• Species: Human
• Form: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
• Purity: >80%
• Concentration: 0.1 ug/ul
• Specific Activity: 120 RLU/min/ng
• Sequences: 1-482
• Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Pathways: Signaling events mediated by HDAC Class I; NAD-dependent histone deacetylase activity (H3-K14 specific)

Gene Information

• Gene Name: HDAC10 histone deacetylase 10 [ Homo sapiens ]
• Official Symbol: HDAC10
• Synonyms: HDAC10; histone deacetylase 10; HD10; MGC149722; DKFZp761B039; histone deacetylase 10; OTTHUMP00000042162; OTTHUMP00000196674; OTTHUMP00000196675; OTTHUMP00000197621
• Gene ID: 83933
• mRNA Refseq: NM_032019
• Protein Refseq: NP_114408
• MIM: 608544
• UniProt ID: Q969S8
• Chromosome Location: 22q13
• Function: NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); enzyme binding; histone deacetylase activity; histone deacetylase activity (H3-K16 specific); histone deacetylase binding; hydrolase activity; protein binding; protein deacetylase activity