Recombinant Human HK1 Protein (Phe80-Met215), His tagged
Cat.No. : | HK1-2351H |
Product Overview : | Recombinant human HK1 (Phe80-Met215) protein fused with His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Catalyzes the phosphorylation of various hexoses, such as D-glucose, D-glucosamine, D-fructose, D-mannose and 2-deoxy-D-glucose, to hexose 6-phosphate (D-glucose 6-phosphate, D-glucosamine 6-phosphate, D-fructose 6-phosphate, D-mannose 6-phosphate and 2-deoxy-D-glucose 6-phosphate, respectively). Does not phosphorylate N-acetyl-D-glucosamine. Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate. Involved in innate immunity and inflammation by acting as a pattern recognition receptor for bacterial peptidoglycan. When released in the cytosol, N-acetyl-D-glucosamine component of bacterial peptidoglycan inhibits the hexokinase activity of HK1 and causes its dissociation from mitochondrial outer membrane, thereby activating the NLRP3 inflammasome |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 16.34 kDa |
Protein Length : | Phe80-Met215 |
Purity : | >90 % as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | HK1 hexokinase 1 [ Homo sapiens (human) ] |
Official Symbol : | HK1 |
Synonyms : | HK1; hexokinase 1; hexokinase-1; HK I; glycolytic enzyme; hexokinase type I; brain form hexokinase; HKI; HXK1; HK1-ta; HK1-tb; HK1-tc; |
Gene ID : | 3098 |
mRNA Refseq : | NM_000188 |
Protein Refseq : | NP_000179 |
MIM : | 142600 |
UniProt ID : | P19367 |
Products Types
◆ Recombinant Protein | ||
HK1-318H | Recombinant Human HK1 Protein, MYC/DDK-tagged | +Inquiry |
HK1-1072H | Recombinant Human HK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
HK1-2681H | Recombinant Human HK1 protein(21-460 aa), C-His-tagged | +Inquiry |
Hk1-1129M | Recombinant Mouse Hk1 Protein, MYC/DDK-tagged | +Inquiry |
HK1-1141H | Active Recombinant Human HK1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
HK1-794HCL | Recombinant Human HK1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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