Active Recombinant Human IL1A Protein
Cat.No. : | IL1A-02H |
Product Overview : | Recombinant Human IL1A Protein (Ser113-Ala271) without tag was exoressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. |
Source : | E. coli |
Species : | Human |
Bio-activity : | Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. Symons, J.A. et al. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 272. The ED50 for this effect is 1‑6 pg/mL. |
Molecular Mass : | 18 kDa |
Protein length : | 13-271 |
N-terminal Sequence Analysis : | Ser113 |
Endotoxin : | < 0.10 EU/μg of the protein by the LAL method. |
Purity : | > 97%, by SDS-PAGE under reducing conditions and visualized by silver stain |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. |
Reconstitution : | Reconstitute at 10 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
Shipping : | The product is shipped at ambient temperature. |
Gene Name : | IL1A interleukin 1 alpha [ Homo sapiens (human) ] |
Official Symbol : | IL1A |
Synonyms : | IL1A; interleukin 1 alpha; IL1; IL-1A; IL1F1; IL1-ALPHA; IL-1 alpha; interleukin-1 alpha; hematopoietin-1; preinterleukin 1 alpha; pro-interleukin-1-alpha |
Gene ID : | 3552 |
mRNA Refseq : | NM_000575 |
Protein Refseq : | NP_000566 |
MIM : | 147760 |
UniProt ID : | P01583 |
Products Types
◆ Recombinant Protein | ||
Il1a-54M | Active Recombinant Mouse Il1a Protein (Ser115-Ser270), C-His tagged, Animal-free, Carrier-free | +Inquiry |
Il1a-098M | Active Recombinant Mouse Il1a Protein | +Inquiry |
IL1A-5432P | Recombinant Pig Interleukin 1, Alpha | +Inquiry |
IL1A-159H | Recombinant Active Human IL1A Protein, His-tagged(C-ter) | +Inquiry |
IL1A-4502M | Recombinant Mouse IL1A Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IL1A-2911HCL | Recombinant Human IL1A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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