Recombinant Human IL2RB Protein, His\Avi-tagged

• Cat.No.: IL2RB-201H
• Product Overview: Biotinylated Recombinant Human Interleukin-2 Receptor subunit beta is produced by our Mammalian expression system and the target gene encoding Ala27-Asp239 is expressed with a 6His, Avi tag at the C-terminus.

Specification

• Description: Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.
• Source: Human Cells
• Species: Human
• Tag: His\Avi
• Form: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• AA Sequence: Ala27-Asp239
• Endotoxin: Less than 0.1 ng/ug (1 EU/ug).
• Shipping: Ambient

Gene Information

• Gene Name: IL2RB interleukin 2 receptor subunit beta [ Homo sapiens (human) ]
• Official Symbol: IL2RB
• Synonyms: IL-2R beta; IL-2 R beta; IL-2RB; Interleukin-2 receptor subunit beta; IL-2 receptor subunit beta; IL-2R subunit beta; High affinity IL-2 receptor subunit beta; CD122; IMD63; IL15RB; P70-75
• Gene ID: 3560
• mRNA Refseq: NM_000878.5
• Protein Refseq: NP_000869.1
• MIM: 146710
• UniProt ID: P14784