Recombinant Human MGAT4A Protein (AA 33-535), N-6×His/GFP tagged

• Cat.No.: MGAT4A-07H
• Product Overview: Recombinant Human MGAT4A Protein (AA 33-535) with N-6×His/GFP tag was expressed in HEK293.

Specification

• Description: This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme B, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation.
• Source: HEK293
• Species: Human
• Tag: N-6×His, GFP
• Molecular Mass: ~89 kDa
• Protein Length: AA 33-535
• AA Sequence: KLIAYQREFLALKERLRIAEHRISQ RSSELNTIVQQFKRVGAETNGSKDA LNKFSDNTLKLLKELTSKKSLQVPS IYYHLPHLLKNEGSLQPAVQIGNGR TGVSIVMGIPTVKREVKSYLIETLH SLIDNLYPEEKLDCVIVVFIGETDI DYVHGVVANLEKEFSKEISSGLVEV ISPPESYYPDLTNLKETFGDSKERV RWRTKQNLDYCFLMMYAQEKGIYYI QLEDDIIVKQNYFNTIKNFALQLSS EEWMILEFSQLGFIGKMFQAPDLTL IVEFIFMFYKEKPIDWLLDHILWVK VCNPEKDAKHCDRQKANLRIRFRPS LFQHVGLHSSLSGKIQKLTDKDYMK PLLLKIHVNPPAEVSTSLKVYQGHT LEKTYMGEDFFWAITPIAGDYILFK FDKPVNVESYLFHSGNQEHPGDILL NTTVEVLPFKSEGLEISKETKDKRL EDGYFRIGKFENGVAEGMVDPSLNP ISAFRLSVIQNSAVWAILNEIHIKK ATN
• Purity: >85%, by SDS-PAGE as visualized by Coomassie Blue Staining
• Stability: 6 months if stored at -80 centigrade. Avoid repeated freeze thaws.
• Concentration: 1 mg/mL
• Storage Buffer: Supplied as a 0.2 μm filtered solution in 20mM HEPES pH 7.0 and 100mM NaCl buffer, with 10% Glycerol.
• Preservative: 0.05 % NaN3
• Shipping: This product is shipped as 0.2μm filtered product on dry ice.

Gene Information

• Gene Name: MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A [ Homo sapiens (human) ]
• Official Symbol: MGAT4A
• Synonyms: MGAT4A; mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A; mannosyl (alpha 1,3 ) glycoprotein beta 1,4 N acetylglucosaminyltransferase, isoenzyme A; alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A; GnT 4a; GnT Iva; glcNAc-T IVa; N-acetylglucosaminyltransferase IVa; UDP-GlcNAc:a-1,3-D-mannoside b-1,4-acetylglucosaminyltransferase IV; alpha-1,3-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa; UDP-N-acetylglucosamine:alpha1,3-d-mannoside beta1,4-N-acetylglucosaminyltransferase; mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isoenzyme A; UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa; GNT-IV; GnT-4a; GNT-IVA
• Gene ID: 11320
• mRNA Refseq: NM_012214
• Protein Refseq: NP_036346
• MIM: 604623
• UniProt ID: Q9UM21