Recombinant Human MICB Protein, Fc/His-tagged


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Recombinant Human MICB Protein, Fc/His-tagged

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Cat.No. : MICB-2051H
Product Overview : Recombinant Human MICB Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala23-Gly298) of human MICB (Accession #NP_005922.2) fused with an Fc, 6×His tag at the C-terminus.
Description : MHC class I polypeptide-related sequence B (MICB) is a protein that is encoded by the MICB gene located within MHC locus. MICB is related to MHC class I and has similar domain structure, which is made up of external α1α2α3 domain, transmembrane segment and C-terminal cytoplasmic tail. MICB is a stress-induced ligand for NKG2D receptor. The heat shock stress pathway is involved in the regulation of MICB expression as transcription of MICB is regulated by promoter heat shock element.
Source : HEK293
Species : Human
Tag : Fc/His
Form : Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5 % mannitol.
Protein length : Ala23-Gly298
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : > 90% as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name : MICB MHC class I polypeptide-related sequence B [ Homo sapiens ]
Official Symbol : MICB
Synonyms : MICB; MHC class I polypeptide-related sequence B; PERB11.2; MIC-B; MHC class I mic-B antigen; stress inducible class I homolog; MHC class I chain-related protein B; MHC class I-like molecule PERB11.2-IMX;
Gene ID : 4277
mRNA Refseq : NM_005931
Protein Refseq : NP_005922
MIM : 602436
UniProt ID : Q29980

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