Active Recombinant Human MINK1 Protein, GST/His-tagged

• Cat.No.: MINK1-5342H
• Product Overview: Human MINK1 (NM_015716.3, 1 a.a. - 320 a.a.) full-length recombinant protein with GST-His tag expressed in Sf9 cells.

Specification

• Description: This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq
• Source: Insect cell
• Species: Human
• Tag: GST/His
• Form: Liquid
• Bio-activity: 95 pmol/μg x min
• Molecular Mass: 67.100 kDa
• Applications: Functional Study
  SDS-PAGE
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Concentration: 0.297 μg/μL
• Storage Buffer: In 50 mM Hepes, 100 mM NaCl, pH 7.5. (5 mM DTT, 15 mM reduced glutathione, 20% glycerol)

Gene Information

• Gene Name: MINK1 misshapen-like kinase 1 [ Homo sapiens ]
• Official Symbol: MINK1
• Synonyms: MINK1; misshapen-like kinase 1; misshapen like kinase 1 (zebrafish); B55; MAP4K6; MINK; misshapen/NIK related kinase; YSK2; ZC3; MEKKK 6; MEK kinase kinase 6; GCK family kinase MINK; misshapen/NIK-related kinase; MAPK/ERK kinase kinase kinase 6; serine/threonine protein kinase; mitogen-activated protein kinase kinase kinase kinase 6; hMINK; hMINKbeta; MGC21111
• Gene ID: 50488
• mRNA Refseq: NM_001024937
• Protein Refseq: NP_001020108
• MIM: 609426
• UniProt ID: Q8N4C8