Recombinant Human MLYCD Protein, GST-tagged

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Recombinant Human MLYCD Protein, GST-tagged

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Cat.No. : MLYCD-5401H
Product Overview : Human MLYCD full-length ORF ( NP_036345.2, 1 a.a. - 493 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 81.4 kDa
AA Sequence : MRGFGPGLTA RRLLPLRLPP RPPGPRLASG QAAGALERAM DELLRRAVPP TPAYELREKT PAPAEGQCAD FVSFYGGLAE TAQRAELLGR LARGFGVDHG QVAEQSAGVL HLRQQQREAA VLLQAEDRLR YALVPRYRGL FHHISKLDGG VRFLVQLRAD LLEAQALKLV EGPDVREMNG VLKGMLSEWF SSGFLNLERV TWHSPCEVLQ KISEAEAVHP VKNWMDMKRR VGPYRRCYFF SHCSTPGEPL VVLHVALTGD ISSNIQAIVK EHPPSETEEK NKITAAIFYS ISLTQQGLQG VELGTFLIKR VVKELQREFP HLGVFSSLSP IPGFTKWLLG LLNSQTKEHG RNELFTDSEC KEISEITGGP INETLKLLLS SSEWVQSEKL VRALQTPLMR LCAWYLYGEK HRGYALNPVA NFHLQNGAVL WRINWMADVS LRGITGSCGL MANYRYFLEE TGPNSTSYLG SKIIKASEQV LSLVAQFQKN SKL
Applications : Antibody Production
Functional Study
Compound Screening
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : MLYCD malonyl-CoA decarboxylase [ Homo sapiens ]
Official Symbol : MLYCD
Synonyms : MLYCD; malonyl-CoA decarboxylase; malonyl-CoA decarboxylase, mitochondrial; hMCD; MCD; malonyl coenzyme A decarboxylase; MGC59795;
Gene ID : 23417
mRNA Refseq : NM_012213
Protein Refseq : NP_036345
MIM : 606761
UniProt ID : O95822

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