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Recombinant Human MRPL43 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : MRPL43-6638H
Product Overview : MRPL43 MS Standard C13 and N15-labeled recombinant protein (NP_789762) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 23.4 kDa
AA Sequence : MTARGTPSRFLASVLHNGLGRYVQQ LQRLSFSVSRDGASSRGAREFVERE VIDFARRNPGVVIYVNSRPCCVPRV VAEYLNGAVREESIHCKSVEEISTL VQKLADQSGLDVIRIRKPFHTDNPS IQGQWHPFTNKPTTFRGLRPREVQD PAPAQDTGLRLSAVAPQILLPGWPD PPDLPTVDPISSSLTSAPAPMLSAV SCLPIVPALTTVCSATRTRPLEQKL ISEEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : MRPL43 mitochondrial ribosomal protein L43 [ Homo sapiens (human) ]
Official Symbol : MRPL43
Synonyms : MRPL43; mitochondrial ribosomal protein L43; 39S ribosomal protein L43, mitochondrial; bMRP36a; L43mt; MRP-L43; mitochondrial ribosomal protein bMRP36a; MGC17989; MGC48892;
Gene ID : 84545
mRNA Refseq : NM_176792
Protein Refseq : NP_789762
MIM : 611848
UniProt ID : Q8N983

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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