Recombinant Human PDK1 Protein, MYC/DDK-tagged

• Cat.No.: PDK1-824H
• Product Overview: Recombinant human PDK1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013].
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 49.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: pyruvate dehydrogenase kinase 1[ Homo sapiens ]
• Official Symbol: PDK1
• Synonyms: mitochondrial pyruvate dehydrogenase kinase isoenzyme 1; pyruvate dehydrogenase kinase, isoenzyme 1; pyruvate dehydrogenase kinase, isozyme 1
• Gene ID: 5163
• mRNA Refseq: NM_002610.3
• Protein Refseq: NP_002601
• MIM: 602524
• UniProt ID: Q15118