Recombinant Human ULBP1 Protein (26-215), C-Fc/Avi-tagged

• Cat.No.: ULBP1-05H
• Product Overview: Recombinant Human NKG2D ligand 1 is produced by our Mammalian expression system and the target gene encoding Gly26-Pro215 is expressed with a Fc tag at the C-terminus.

Specification

• Description: The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.
• Source: Human Cells
• Species: Human
• Tag: C-Fc
• Protein Length: Gly26-Pro215
• Endotoxin: Less than 0.1 ng/μg (1 EU/μg)
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
• Shipping: Ambient

Gene Information

• Gene Name: ULBP1 UL16 binding protein 1 [ Homo sapiens (human) ]
• Official Symbol: ULBP1
• Synonyms: ULBP1; UL16 binding protein 1; N2DL-1; RAET1I; NKG2DL1; UL16-binding protein 1; NKG2D ligand 1; alcan-beta; retinoic acid early transcript 1I
• Gene ID: 80329
• mRNA Refseq: NM_025218
• Protein Refseq: NP_079494
• MIM: 605697
• UniProt ID: Q9BZM6