Active Recombinant Mouse IL6 Protein
Cat.No. : | IL6-185M |
Product Overview : | Recombinant Mouse IL6 Protein without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin 6 (IL-6) is a cytokine that is expressed by T cells, macrophages, and muscle cells. IL-6 acts to stimulate an immune response upon infection or trauma. IL-6 has both pro-inflammatory and anti-inflammatory functions, is capable of promoting fever, and signals through the cell-surface type I cytokine receptor complex containing the IL-6Ra and gp130 chains. Human IL-6 is active on mouse and rat cells. |
Source : | E. coli |
Species : | Mouse |
Bio-activity : | B9 cell proliferation, ED50≤50 pg/mL |
Molecular Mass : | Monomer, 21.9 kDa (188 aa) |
AA Sequence : | MFPTSQVRRGDFTEDTTPNRPVYTT SQVGGLITHVLWEIVEMRKELCNGN SDCMNNDDALAENNLKLPEIQRNDG CYQTGYNQEICLLKISSGLLEYHSY LEYMKNNLKDNKKDKARVLQRDTET LIHIFNQEVKDLHKIVLPTPISNAL LTDKLESQKEWLRTKTIQFILKSLE EFLKVTLRSTRQT |
Endotoxin : | ≤1 EUs/μg, Kinetic LAL |
Purity : | ≥95%, Reducing and Non-Reducing SDS PAGE |
Stability : | 12 months from date of receipt when stored at -20 to -80 centigrade as supplied. 1 month when stored at 4 centigrade after reconstituting as directed. 3 months when stored at -20 to -80 centigrade after reconstituting as directed. |
Storage : | Storage Prior to Reconstitution: -20 centigrade |
Storage Buffer : | Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA) |
Reconstitution : | Sterile 10 mM HCl at 0.1 mg/mL |
Shipping : | Room temperature |
Instructions : | Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 centigrade and avoid repeat freeze thaws. |
Gene Name : | Il6 interleukin 6 [ Mus musculus (house mouse) ] |
Official Symbol : | IL6 |
Synonyms : | IL6; interleukin 6; interleukin-6; interleukin HP-1; B-cell hybridoma growth factor; Il-6; |
Gene ID : | 16193 |
mRNA Refseq : | NM_031168 |
Protein Refseq : | NP_112445 |
UniProt ID : | P08505 |
Products Types
◆ Lysates | ||
IL6-5224HCL | Recombinant Human IL6 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe dosage and usage of Il6 will vary according to the disease, and generally require individualized regulation by the physician according to the disease situation.
The pharmacokinetic characteristics of Il6 mainly include drug absorption, distribution, metabolism, excretion and other information.
Recombinant Il6 protein has a unique therapeutic advantage in the treatment of multiple myeloma. It can promote the proliferation and differentiation of hematopoietic stem cells and inhibit the growth of tumor cells.
Il6 has specific therapeutic effects for certain diseases, such as rheumatoid arthritis, multiple myeloma and so on.
This protein is widely used in the treatment of rheumatoid arthritis, pneumonia, multiple myeloma, lymphoma, malignant tumors and other diseases.
The effects of Il6 on immune cells are mainly manifested as promoting cell proliferation and differentiation, regulating immune response, etc.
Customer Reviews (3)
Write a reviewAccurate localization and function within the cell.
The binding affinity and affinity constant with the target are high.
Can form a stable micellar structure.
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