Il6

  • Official Full Name

    interleukin 6

  • Overview

    This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011]
  • Synonyms

    IL6; interleukin 6; HGF; HSF; BSF2; IL-6; IFNB2; interleukin-6; CDF; BSF-2; IFN-beta-2; interferon beta-2; interleukin BSF-2; interferon, beta 2; hybridoma growth factor; CTL differentiation factor; B-cell stimulatory factor 2; B-cell differentiation factor;

  • Recombinant Proteins
  • GMP Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Transfected Stable Cell Lines
  • Protein Pre-coupled Magnetic Beads
  • Atlantic Salmon
  • Bovine
  • Canine
  • Cat
  • Cattle
  • Chicken
  • Cotton Rat
  • Cynomolgus
  • Cynomolgus Monkey
  • Dog
  • Equine
  • Ferret
  • Guinea pig
  • Hamster
  • Horse
  • Human
  • Macaca mulatta
  • Mouse
  • Pig
  • Porcine
  • Rabbit
  • Rat
  • Rhesus
  • Rhesus Macaque
  • Rhesus monkey
  • Sheep
  • Zebrafish
  • Barley Grain
  • Cat
  • CHO
  • CHO-K1
  • E.coli
  • HEK293
  • HEK293 cells
  • HEK293F
  • HEK293T
  • Hordeum Vulgare
  • Human Cell
  • Human cells
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Nicotiana Benthamiana
  • P.pastoris
  • Protein Conjugation
  • Rabbit
  • Rat
  • Sf9 Insect Cell
  • Yeast
  • APC
  • Avi
  • His
  • Biotin
  • C
  • Fc
  • mFc
  • 6×His
  • Flag
  • GST
  • His (Fc)
  • His(C
  • ter)
  • His|GST
  • His|T7
  • SUMO
  • HQ
  • Met
  • Myc
  • DDK
  • MYC
  • N/A
  • N
  • No tag
  • Strep II
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL6-8865H Active Recombinant Human IL6,His-tagged Hordeum Vulgare N/A
Human IL6-106H Active Recombinant Human IL6 Nicotiana Benthamiana N/A
Human IL6-128H Active Recombinant Human Interleukin 6 (Interferon, Beta 2) HEK293 N/A
Human IL6-23H Active Recombinant Human IL6 CHO N/A
Human IL6-142H Active Recombinant Human IL6, His-tagged, Animal Free Nicotiana Benthamiana His
Human IL6-1H Active Recombinant Human IL6 Sf9 Insect Cell N/A
Human IL6-311H Active Recombinant Human IL6, MIgG2a Fc-tagged CHO Fc
Human IL6-312H Active Recombinant Human IL6,HIgG1 Fc-tagged, mutant CHO Fc
Human IL6-041H Active Recombinant Human IL6 Protein HEK293 N/A
Human IL6-105H Active Recombinant Human IL6, His-tagged E.coli His
Human IL6-313H Active Recombinant Human IL6, HIgG1 Fc-tagged CHO Fc
Human IL6-28H Active Recombinant Human IL6, His-tagged Barley Grain His
Human IL6-163H Active Recombinant Human Interleukin 6, HIgG1 Fc-tagged CHO Fc
Human IL6-01HG Active GMP Recombinant Human IL6 Protein CHO-K1
Human IL6-3395H Active Recombinant Human IL6 protein(Val30-Met212) E.coli N/A Val30-Met212
Human IL6-12H Recombinant Human IL6 protein E.coli N/A 183
Human IL6-264H Recombinant Human IL6, StrepII-tagged Human Cell Strep II 30-212, 183 a.a.
Human IL6-554H Recombinant Human IL6 protein, His-tagged HEK293F His Val30~Met212
Human IL6-1558H Recombinant human IL6, Active, His-tagged Nicotiana Benthamiana His
Human IL6-323H Recombinant Human IL6, His-tagged E.coli His
Human IL6-78H Recombinant Human IL-6 Yeast N/A
Human IL6-62H Recombinant Human Interleukin 6 (interferon, beta 2) CHO N/A
Human IL6-318H Recombinant Human IL6, Fc-tagged CHO Fc
Human IL6-505H Recombinant Human IL6 protein HEK293 183
Human IL6-363H Recombinant Human Interleukin 6 (interferon, beta 2) P.pastoris N/A
Human IL6-5309H Recombinant Human Interleukin 6 (interferon, beta 2), HQ-tagged Hordeum Vulgare HQ
Human IL6-5224HCL Recombinant Human IL6 293 Cell Lysate HEK293 N/A
Human IL6-1045H Recombinant Human IL6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IL6-4287H Recombinant Human IL6 Protein (Val30-Met212), C-His tagged Mammalian cells C-His Val30-Met212
Human DMABT-H19252 Rat Anti-IL6 Monoclonal Antibody Rat APC
Human CAB11567RH Rabbit Anti-Human Interleukin 6 Monoclonal Antibody Rabbit N/A
Human IL6-068H Active Recombinant Human IL6 Protein E.coli
Human IL6-351I Active Recombinant Human IL6 Protein (185 aa) E.coli 185
Human IL6-210HG Active GMP Recombinant Human IL6 Protein E.coli
Human IL6-001H Recombinant Human IL6 Protein E.coli 29-212
Human IL6-040H Recombinant Human IL6 Protein, non-tagged, Biotinylated HEK293 N/A
Human IL6-24HG Active Recombinant Human IL6 Protein (Pro29-Met212), GMP Grade, Animal-Free E.coli Pro29-Met212
Human IL6-170H Active Recombinant Human IL6 Protein (Val30-Met212), C-His tagged, Animal-free, Carrier-free E.coli C-His Val30-Met212
Human IL6-002H Recombinant Human IL6 Protein, His-tagged E.coli His 29-212
Human IL6-209H Recombinant Active Human IL6 Protein, His-tagged(C-ter) HEK293 His(C-ter) Val30-Met212
Human IL6-1179H Recombinant Human IL6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human IL6-2324H Recombinant Human IL6 Protein, His-tagged E.coli N-His Met1-Ala25+Val30-Met212
Human IL6-213HG Active GMP Recombinant Human IL6 protein HEK293
Human IL6-210H Recombinant Active Human IL6 Protein, Tag Free E.coli Tag Free
Human IL6-09H Active Recombinant Human IL6 Protein, Pre-aliquoted E.coli Pro29-Met212
Human IL6-37H Active Recombinant Human IL6 Protein, Animal Free Human cells
Human IL6-052H Recombinant Human IL6 Mutant (R44M) Protein, Myc/DDK-tagged HEK293 Myc/DDK
Human IL6-196H Active Recombinant Human IL6 Protein E.coli
Human IL6-208H Recombinant Active Human IL6 Protein, His-tagged(C-ter) E.coli His(C-ter)
Human IL6-02H Active Recombinant Human IL6 Protein (30-212aa), N-His-tagged E.coli N-His 30-212aa
Human IL6-44H Recombinant Human IL6 Protein E.coli
Human IL6-236I Active Recombinant Human IL6 Protein CHO
Human IL6-100H Human Interleukin-6 (rDNA derived) Reference standard N/A
Human IL6-0339H Recombinant Human IL6 Protein (A28-M212), Tag Free E.coli No tag A28-M212
Human IL6-4321HG GMP Recombinant Human IL6 protein E.coli N/A 183
Human IL6-2493H Recombinant Human IL6 Protein (Met1-Met212), C-Fc tagged Mammalian cells C-Fc Met1-Met212
Human DMABT-H19253 Rat Anti-IL6 Monoclonal Antibody Rat Biotin
Human IL6-0300H Active Recombinant Human IL6 protein, Avi-His-tagged, Biotinylated HEK293 Avi-His Val30-Met212
Human IL6-1047H Recombinant Human IL6 Protein, GST-tagged E.coli N-GST Pro29-Met212
Human IL6-184H Active Recombinant Human IL6 Protein E.coli
Human IL6-1682H Recombinant Human IL6 Protein, His&GST-tagged E.coli N-His&GST Pro29-Met212
Human IL6-4286H Recombinant Human IL6 Protein (Val30-Met212), C-His and Avi tagged Mammalian cells C-His and Avi Val30-Met212
Human IL6-61H Recombinant Human IL6 Protein E.coli
Human IL6-515H Recombinant Human IL6 Protein, Biotinylated 212
Human IL6-760HFL Recombinant Full Length Human IL6 Protein, C-Flag-tagged Mammalian cells Flag
Human IL6-516H Recombinant Human IL6 Protein 212
Human IL6-0019H Recombinant Human IL6 Protein HEK293 cells
Human IL6-093I Active Recombinant Human IL6 Protein (184 aa) E.coli 184
Human IL6-33HG Recombinant Human IL6 Protein, GMP Grade, Animal-Free E.coli
Human IL6-1179H-B Recombinant Human IL6 Protein Pre-coupled Magnetic Beads HEK293
Human IL6-251H Recombinant Human IL6 Protein (Val30-Met212), C-mFc and 6×His-tagged HEK293 C-mFc and 6×His Val30-Met212
Human IL6-252H Active Recombinant Human IL6 Protein E.coli Tag Free
Human IL6-4285H Recombinant Human IL6 Protein (Met1-Met212), C-His tagged Mammalian cells C-His Met1-Met212
Mouse IL6-314H Active Recombinant Human IL6, MIgG2a Fc-tagged, mutant CHO Fc
Mouse Il6-657M Active Recombinant Mouse Il6 protein(Phe25-Thr211) E.coli N/A Phe25-Thr211
Mouse Il6-320M Active Recombinant Mouse Il6, Fc-tagged HEK293 Fc
Mouse Il6-321M Active Recombinant Mouse Il6, Fc-tagged CHO Fc
Mouse IL6-001M Active Recombinant Mouse IL6, MIgG2a Fc-tagged CHO Fc
Mouse Il6-01M Active Recombinant Mouse Il6 Protein, His-Tagged E.coli His
Mouse Il6-76M Recombinant Mouse Interleukin 6 E.coli N/A
Mouse Il6-8668M Recombinant Mouse Il6, None tagged E.coli N/A
Mouse IL6-605M Recombinant Mouse interleukin 6 (interferon, beta 2), His-tagged E.coli His
Mouse Il6-37M Recombinant Mouse Il6 protein, His-tagged Insect Cell His
Mouse Il6-12M Recombinant Mouse Il6 protein E.coli N/A 188
Mouse Il6-490M Recombinant Mouse Il6 protein, His-tagged HEK293F His Phe25~Thr211
Mouse Il6-113M Active Recombinant Mouse Il6 Protein E.coli
Mouse DMABT-H18984 Rat Anti-IL6 Monoclonal Antibody Rat APC
Mouse Il6-136M Mouse Interleukin-6 (rDNA derived) Reference standard N/A
Mouse DMABT-H18985 Rat Anti-IL6 Monoclonal Antibody Rat Biotin
Mouse Il6-115M Recombinant Mouse Il6 Protein E.coli
Mouse Il6-7246M Recombinant Mouse Il6 Protein, His-tagged E.coli His 25-211
Mouse Il6-044MG Active GMP Recombinant Mouse Il6 protein HEK293 DNA sequence encoding Mouse IL-6(NP_112445.1) was expressed with His tag at the C-terminal.
Mouse Il6-237I Active Recombinant Mouse Il6 Protein, His-tagged CHO His
Mouse Il6-214M Recombinant Mouse Il6 Protein, His-tagged E.coli His
Mouse Il6-61M Active Recombinant Mouse Il6 Protein (Phe25-Thr211), C-His tagged, Animal-free, Carrier-free E.coli C-His Phe25-Thr211
Mouse Il6-024I Active Recombinant Mouse Il6 Protein (187 aa) E.coli 187
Mouse Il6-116M Recombinant Mouse Il6 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse IL6-0301M Recombinant Mouse IL6 protein, Avi-His-tagged, Biotinylated HEK293 Avi-His Phe25-Thr211
Mouse Il6-114M Active Recombinant Mouse Il6 Protein E.coli
Mouse IL6-2003M Recombinant Mouse IL6 Protein E.coli N/A
Mouse IL6-0302M Active Recombinant Mouse IL6 protein, His-tagged HEK293 His Phe25-Thr211
Mouse IL6-185M Active Recombinant Mouse IL6 Protein E.coli
Mouse IL6-68M Recombinant Mouse IL6 Protein E.coli
Mouse Il6-4057M Recombinant Mouse Il6 Protein (Phe25-Thr211), C-His tagged E.coli C-His Phe25-Thr211
Mouse Il6-212M Recombinant Active Mouse IL6 Protein, His-tagged(C-ter) E.coli His(C-ter)
Rat Il6-481R Recombinant Rat Il6 protein, His-tagged HEK293F His Phe25~Thr211
Rat Il6-98R Recombinant Rat Interleukin 6 E.coli N/A
Rat IL6-3049R Recombinant Rat IL6 Protein Mammalian Cell His
Rat Il6-473R Recombinant Rat Il6 protein E.coli N/A 187
Rat IL6-8710R Active Recombinant Rat IL6 protein E.coli N/A Phe25-Thr211
Rat IL6-186R Active Recombinant Rat IL6 Protein E.coli
Rat IL6-2704R Recombinant Rat IL6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Il6-176I Active Recombinant Rat Il6 Protein HEK293
Rat IL6-2704R-B Recombinant Rat IL6 Protein Pre-coupled Magnetic Beads HEK293
Rhesus monkey IL6-659R Recombinant Rhesus monkey IL6 protein, His-tagged E.coli His Pro27~Met212 (Accession # P51494)
Rabbit IL6-658R Recombinant Rabbit IL6 protein, His & GST-tagged E.coli His/GST Phe27~Thr241
Rabbit IL6-5814R Recombinant Rabbit IL6 protein, His-tagged Yeast His 27-241aa
Rabbit IL6-4372R Recombinant Rabbit IL6 Protein Yeast N/A 188aa
Rabbit IL6-1048R Recombinant Rabbit IL6 Protein, His-tagged HEK293F N-His Phe27-Thr241
Dog IL6-498D Recombinant Dog IL6 protein, His-tagged HEK293F His Phe21~Met207
Dog IL6-654D Recombinant Dog IL6 protein, His & T7-tagged E.coli His/T7 Ala18~Met207 (Accession # P41323)
Dog IL6-1045D Recombinant Dog IL6 Protein, His-tagged E.coli N-His Ala18-Met207
Dog IL6-1584D Recombinant Dog IL6 Protein (Met1-Met207), C-His tagged E.coli C-His Met1-Met207
Atlantic Salmon IL6-4394A Recombinant Atlantic Salmon IL6 Protein Yeast N/A 202aa
Bovine IL6-241B Active Recombinant Bovine Interleukin 6 (Interferon, Beta 2) Yeast N/A
Canine IL6-144C Recombinant Canine IL6 protein, His-tagged Insect Cell His
Canine IL6-244C Recombinant Canine Interleukin 6 (Interferon, Beta 2) Yeast N/A
Cat IL6-598C Recombinant Cat Interleukin 6 (interferon, beta 2) Cat N/A
Cattle IL6-1051C Recombinant Cattle IL6 Protein, His-tagged E.coli N-His Pro29-Lys208
Cotton Rat Il6-392C Active Recombinant Cotton Rat Il6, Met-tagged E.coli Met
Cynomolgus IL6-0299C Active Recombinant Cynomolgus IL6 protein, His-tagged HEK293 His Ala28-Met212
Cynomolgus Monkey IL6-8849C Recombinant Cynomolgus IL6, None tagged E.coli His
Cynomolgus Monkey IL6-326 Recombinant Cynomolgus Monkey IL6 protein Yeast N/A 185 aa
Equine IL6-258E Active Recombinant Equine Interleukin 6 (Interferon, Beta 2) Yeast N/A
Ferret IL6-013F Recombinant Ferret IL6 Protein, Met1-Ile174, C-His tagged HEK293 C-His Met1-Ile174
Guinea pig Il6-2325G Recombinant Guinea pig Il6 Protein, His-tagged HEK293F N-His Phe25-Asn223
Guinea pig Il6-1050G Recombinant Guinea pig Il6 Protein, His-tagged E.coli N-His Phe25-Asn223
Hamster IL6-018H Recombinant Hamster IL6 Protein, Met1-Asn212, C-His tagged HEK293 C-His Met1-Asn212
Horse IL6-1046H Recombinant Horse IL6 Protein, His-tagged E.coli N-His Thr28-Met208
Horse IL6-3219H Recombinant Horse IL6 protein, His-SUMO-tagged E.coli His-SUMO Thr28~Met208
Macaca mulatta IL6-5433M Recombinant Macaca mulatta Interleukin 6 (interferon, beta 2) E.coli N/A
Porcine IL6-01P Active GMP Recombinant Porcine IL6 Protein, His-Tagged E.coli His
Rhesus IL6-560R Recombinant Rhesus IL6 protein E.coli N/A 186
Rhesus Macaque IL6-2254R Recombinant Rhesus monkey IL6 Protein, His-tagged Mammalian Cell His
Rhesus Macaque IL6-2075R Recombinant Rhesus Macaque IL6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque IL6-2075R-B Recombinant Rhesus Macaque IL6 Protein Pre-coupled Magnetic Beads HEK293
Sheep IL6-655S Recombinant Sheep IL6 protein, His-tagged E.coli His Gly30~Lys208 (Accession # P29455)
Sheep IL6-3106S Recombinant Sheep IL6 protein, GST-tagged E.coli GST 30-208aa
Sheep IL6-5451S Recombinant Sheep IL6 protein, His-tagged Yeast His 30-208aa
Zebrafish IL6-8236Z Recombinant Zebrafish IL6 Mammalian Cell His
Zebrafish il6-23Z Recombinant Zebrafish il6 Protein Yeast N/A
Pig Il6-16S Active Recombinant Swine Il6 Yeast N/A
Pig IL6-29S Active Recombinant Swine IL-6 Yeast N/A
Pig IL6-85P Recombinant Porcine Interleukin 6 E.coli N/A
Pig IL6-474P Recombinant Pig IL6 protein, His-tagged HEK293F His Gly30~Met212
Pig IL6-1025P Active Recombinant Pig IL6 protein E.coli N/A Pro29-Met212
Pig IL6-211P Recombinant Active Pig IL6 Protein, His-tagged(C-ter) E.coli His(C-ter)
Pig IL6-1049P Recombinant Pig IL6 Protein, His-tagged E.coli N-His Pro29-Met212
Pig IL6-213P Active Recombinant Pig IL6 Protein (Arg31-Met212), C-His tagged, Animal-free, Carrier-free E.coli C-His Arg31-Met212
Chicken IL6-12C Recombinant Chicken IL6 Protein Yeast N/A
Chicken IL6-597C Recombinant Chicken Interleukin 6 (interferon, beta 2), His-tagged E.coli His
Chicken IL6-6196C Recombinant Chicken IL6 Mammalian Cell His
Chicken IL6-2818C Recombinant Chicken IL6 Protein, His-tagged, OVA Conjugated Protein Conjugation N-His Asp54-Leu71
Chicken IL6-1052C Recombinant Chicken IL6 Protein, His-tagged HEK293F N-His Gln87-Ala241
Chicken IL6-1053C Recombinant Chicken IL6 Protein, His-tagged E.coli N-His Gln87-Ala241
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource
  • Il6 Related Signal Pathway

Il6 involved in several pathways and played different roles in them. We selected most pathways Il6 participated on our site, such as Cytokine-cytokine receptor interaction, HIF- signaling pathway, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Il6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionINHBE;CCL23;CRFB2;LIFRA;TNFSF13;CTF1;LTA;NGFRB;CXCR5
HIF- signaling pathwayTFRC;CAMK2D;FLT1;ANGPT1;IGF1R;VEGFA;ENO3;NOX1;TCEB1
FoxO signaling pathwayIKBKB;FOXO4;FOXO1B;PIK3R3B;HOMER1;MAP2K2;CDKN1BA;INSRA;FOXO3
PIK-Akt signaling pathwayTP53;FGF9;FGF5;EIF4E2;PHLPP2;ITGA8;CCNE2;RAF1;KRAS
Toll-like receptor signaling pathwayLY96;IL8L1;TLR5;IL12BA;TLR4BB;TLR1LB;CXCL10;MAP2K2B;TRAF3
NOD-like receptor signaling pathwayCASP1;MAPK13;TAB2;HSP90AA1.1;MAPK3;HSP90B1;NAIP1;Ccl12;CARD18
Cytosolic DNA-sensing pathwayTREX1;IFI202B;IL18;IFNA6;RELA;POLR1C;IFNA13;Ifna11;POLR2H
Jak-STAT signaling pathwayGH1;LEPA;IL10RB;IL12B;IFNA7;TSLP;CSF3R;HRAS;PTPN11
Hematopoietic cell lineageCD3G;ITGA3;Cd24a;GM-CSF;IL3;Itga10&Itgb1;CD14;GM13305;CD37
TNF signaling pathwayFADD;PIK3R3;MAPK9;CCL5;TRAF3;CCL2;PIK3CD;PGAM5;CCL20
Intestinal iHLA-DOA;H2-AA;H2-AB1;MHC2DEB;HLA-DRA;Il2;HLA-DOB;Icosl;TNFRSF17
ne network for IgA productionICOS;IL4;HLA-DRB3;HLA-DRA;CD28;HLA-DMB;LTBR;Il2;HLA-DRB1
Insulin resistanceFOXO1B;PRKAB1;PPP1R3CB;FOXO1;RPS6KA3;INSRB;PRKAB1B;PTPN11A;PRKAG2
Non-alcoholic fatty liver disease (NAFLD)COX7A2;NDUFA7;TGFB1;SDHC;ERN1;PRKAG2;UQCRC2;PIK3CD;NDUFS1
Prion diseasesC8B;MAP2K1;NCAM1;IL6;C8A;C9;IL1B;STIP1;PRNP
Salmonella infectionROCK2B;MAPK3;CXCL1;MAPK1;IL-8;NOS2A;MAPK13;MAPK12A;ACTB2
PertussisMAPK8;IL23;TRAF6;IL-8;IRF8;Itgam&Itgb2;MAPK12;CD14;Hc
LegionellosisCASP9;TLR5;IL6;BNIP3;APAF1;IL18;PYCARD;CASP1;Casp3
Chagas disease (American trypanosomiasis)PIK3R1;AKT1;PLCB1;IL12A;PLCB3;TGFB1;PPP2CB;GNAS;LOC100033925
African trypanosomiasisTLR9;APOA1;HPR;IL1B;IL6;GNAQ;PLCB3;IL18;IDO2
MalariaMYD88;TGFB3;ICAM1;CD40;IL1B;GYPB;HBA-A2;DARC;TNF
AmoebiasisPIK3R2;PIK3R3;C8B;PIK3CB;CD1d1;COL4A4;GNA14;PLCB3;COL1A2
TuberculosisBAD;CORO1A;Itgam&Itgb2;Il23a; Il12b;CLEC4M;MAPK10;IFNA8;SYK;Pla2r1
Hepatitis BCCND1;MAPK8;IFNA7;IFNA10;HBXIP;PIK3CB;ATF4;Ifna15;MAPK3
MeaslesIL2RG;HSPA1A;IFNAR1;STAT1;IRAK4;RELA;EIF2AK3;IRAK1;CD209C
Influenza APLG;MAPK1;IFNA21;RSAD2;DNAJC3;IFNA1;HSPA1L;NFKBIA;OAS1A
HTLV-I infectionGSK3B;ATF1;HLA-DPB1;ITGB2;ANAPC11;MAP2K4;SFPI1;PPP3CA;SMAD2
Herpes simplex infectionIFNG;TLR9;HMGN1;PVRL2;IL12BA;OAS3;IFIH1;CDC34;SRSF5A
Pathways in cancerGNAI3;RASGRP3;ROCK1;IL-8;FLT3LG;CXCL12;ITGA2;HDAC2;GSK3B
Transcriptional misregulation in cancerHIST2H3A;KDM6A;NCOR1;ETV4;ETV7;NFKB1;SSX1;DOT1L;SLC45A3
Inflammatory bowel disease (IBD)STAT4;IL18RAP;HLA-DRA;IL12B;TGFB2;MAF;Il4ra;HLA-DOB;HLA-DMB
Rheumatoid arthritisCCL3L1;CD80;Ctsl;HLA-DMB;TLR4;Ccl12;ITGAL;VEGFA;HLA-DRB4
Graft-versus-host diseaseHLA-DPA1;FAS;HLA-A;IL1A;KIR3DL1;HLA-DRA;CD86;HLA-DPB1;H2-AA
Hypertrophic cardiomyopathy (HCM)SGCG;CACNB2;ITGA7;SGCB;CACNG3;PRKAA2;ACTC1;ITGB3;MYL3

Il6 has several biochemical functions, for example, cytokine activity, growth factor activity, interleukin-6 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Il6 itself. We selected most functions Il6 had, and list some proteins which have the same functions with Il6. You can find most of the proteins on our site.

Function Related Protein
cytokine activityCcl27a;CCL6;SCGB3A1;Il1f8;GREM1;SLURP1;CMTM5;LEFTY2;IL37
growth factor activityIL34;BMP7B;LACRT;FGF12A;PDGFAA;IGF1;FGF10B;NDR1;CLCF1
interleukin-6 receptor bindingADAM17;IL6;CNTF;ERAP1;PYCARD
contributes_to interleukin-6 receptor bindingIl6ra;IL6ST;IL6R;IL6
protein bindingTBC1D16;PIK3R6;CA8;ZZZ3;CD1A;NAPG;JAK2;PDIA4;GOLGA2

Il6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il6 here. Most of them are supplied by our site. Hope this information will be useful for your research of Il6.

IL6R; ZBTB16; HRH1; IL6ST; SH3GL2

  • Q&As
  • Reviews

Q&As (6)

Ask a question
What is the dosage and usage of Il6? 07/15/2022

The dosage and usage of Il6 will vary according to the disease, and generally require individualized regulation by the physician according to the disease situation.

What are the pharmacokinetic properties of Il6? 06/16/2022

The pharmacokinetic characteristics of Il6 mainly include drug absorption, distribution, metabolism, excretion and other information.

Does Il6 have advantages in the treatment of multiple myeloma? 04/22/2022

Recombinant Il6 protein has a unique therapeutic advantage in the treatment of multiple myeloma. It can promote the proliferation and differentiation of hematopoietic stem cells and inhibit the growth of tumor cells.

Does Il6 have specific therapeutic effects for certain diseases? 05/27/2020

Il6 has specific therapeutic effects for certain diseases, such as rheumatoid arthritis, multiple myeloma and so on.

In which diseases is Il6 widely used? 11/20/2019

This protein is widely used in the treatment of rheumatoid arthritis, pneumonia, multiple myeloma, lymphoma, malignant tumors and other diseases.

What is the effect of Il6 on immune cells? 05/21/2019

The effects of Il6 on immune cells are mainly manifested as promoting cell proliferation and differentiation, regulating immune response, etc.

Customer Reviews (3)

Write a review
Reviews
03/05/2022

    Accurate localization and function within the cell.

    01/31/2021

      The binding affinity and affinity constant with the target are high.

      03/12/2020

        Can form a stable micellar structure.

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