Recombinant Mouse Mx1 protein, His & GST-tagged

• Cat.No.: Mx1-1887M
• Product Overview: Recombinant Mouse Mx1 aa. (Gly43~Leu308 (Accession # P09922)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Mouse
• Source: E.coli
• Tag: GST&His
• Protein Length: Gly43~Leu308
• Description: This gene encodes a member of the Mx protein family of large GTPases, and functions in the innate immunity system. Interferon alpha/beta treatment or viral infection induces expression of this protein, which subsequently accumulates in the cytoplasm and inhibits viral replication. It has been shown to confer resistance to the influenza virus. This gene produces a functional protein in some feral mouse strains, whereas some inbred mouse strains including the strain of the reference genome, C57BL/6J, contain a deletion or a nonsense mutation that results in a non-functional gene product.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 56.1kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 5.8

Gene Information

• Gene Name: Mx1 MX dynamin-like GTPase 1 [ Mus musculus (house mouse) ]
• Official Symbol: Mx1
• Synonyms: Mx1; MX dynamin-like GTPase 1; Mx; Mx-1; AI893580; interferon-induced GTP-binding protein Mx1; myxoma resistance protein 1; myxovirus (influenza virus) resistance 1; myxovirus (influenza) resistance 1 polypeptide
• Gene ID: 17857
• mRNA Refseq: NM_010846.1
• Protein Refseq: NP_034976.1
• UniProt ID: P09922