Recombinant Mouse Nek11 Protein, Myc/DDK-tagged

• Cat.No.: Nek11-4367M
• Product Overview: Purified recombinant protein of mouse full-length NIMA (never in mitosis gene a)-related expressed kinase 11 (Nek11), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 72.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Nek11 NIMA (never in mitosis gene a)-related expressed kinase 11 [ Mus musculus (house mouse) ]
• Official Symbol: Nek11
• Synonyms: NEK11; NIMA (never in mitosis gene a)-related expressed kinase 11; serine/threonine-protein kinase Nek11; NIMA-related kinase 11; nimA-related protein kinase 11; never in mitosis A-related kinase 11; 4932416N14Rik
• Gene ID: 208583
• mRNA Refseq: NM_172461
• Protein Refseq: NP_766049
• UniProt ID: Q8C0Q4