PRODUCTS

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

See All N Products

Specification Related Products

Cat.No. :	N-130V
Product Overview :	Recombinant SARS Coronavirus Nucleoprotein (2-422aa), fused to His-tag at N-terminus, was expressed in mammalian HEK293 cells and purified by immobilised metal affinity and ion exchange chromatography.
Description :	Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Source :	HEK293
Species :	SARS-CoV
Tag :	His
Form :	Liquid. 50mM HEPES, pH8.0, 280mM NaCl.
Protein length :	421
Applications :	Vaccine research and immunoassay development.
Storage :	Store at -80 centigrade, Avoid freeze/thaw cycle.
Concentration :	1.30 mg/ml
Shipping :	Dry Ice.
Synonyms :	GU280_gp10