| Species : |
SARS-CoV |
| Source : |
HEK293 |
| Protein Length : |
421 |
| Description : |
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
| Form : |
Liquid. 50mM HEPES, pH8.0, 280mM NaCl. |
| Applications : |
Vaccine research and immunoassay development. |
| Storage : |
Store at -80 centigrade, Avoid freeze/thaw cycle. |
| Concentration : |
1.30 mg/ml |
| Shipping : |
Dry Ice. |
