Recombinant SARS Coronavirus Nucleoprotein, His-tagged N-130V

Recombinant SARS Coronavirus Nucleoprotein, His-tagged


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Recombinant SARS Coronavirus Nucleoprotein, His-tagged

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Cat.No. : N-130V
Product Overview : Recombinant SARS Coronavirus Nucleoprotein (2-422aa), fused to His-tag at N-terminus, was expressed in mammalian HEK293 cells and purified by immobilised metal affinity and ion exchange chromatography.
Description : Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Source : HEK293
Species : SARS-CoV
Tag : His
Form : Liquid. 50mM HEPES, pH8.0, 280mM NaCl.
Protein length : 421
Applications : Vaccine research and immunoassay development.
Storage : Store at -80 centigrade, Avoid freeze/thaw cycle.
Concentration : 1.30 mg/ml
Shipping : Dry Ice.
Synonyms : GU280_gp10

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